EP 2094736 A1 20090902 - CROSS-LINKED HYALURONIC ACID AND METHOD FOR PRODUCING THE SAME
Title (en)
CROSS-LINKED HYALURONIC ACID AND METHOD FOR PRODUCING THE SAME
Title (de)
VERNETZTE HYALURONSÄURE UND DEREN HERSTELLUNGSVERFAHREN
Title (fr)
ACIDE HYALURONIQUE RÉTICULÉ ET SON PROCÉDÉ DE PRÉPARATION
Publication
Application
Priority
- FR 2007052245 W 20071025
- FR 0609866 A 20061110
Abstract (en)
[origin: WO2008056069A1] The invention relates to a cross-linked hyaluronic acid that can be produced by a method comprising: (a) activating a hyaluronic acid; (b) reacting the activated hyaluronic acid with a cross-linking agent containing an oligo- or polypeptide in a reaction medium at a pH of between 8 and 12 in order to obtain a cross-linked hyaluronic acid; (c) adjusting the pH of the reaction medium to a value between 5 and 7; and (d) precipitating the cross-linked hyaluronic acid in an organic solvent. The invention also relates to the above method, to a hydrogel obtained from said cross-linked hyaluronic acid, and to the use of the cross-linked hyaluronic acid for the production of implants that can essentially be used in plastic surgery.
IPC 8 full level
A61L 31/04 (2006.01); A61L 31/14 (2006.01); C08B 37/08 (2006.01)
CPC (source: EP KR US)
A61L 27/20 (2013.01 - KR); A61L 31/042 (2013.01 - EP US); A61L 31/145 (2013.01 - EP US); A61P 17/02 (2017.12 - EP); C08B 37/003 (2013.01 - KR); C08B 37/0072 (2013.01 - EP US)
C-Set (source: EP US)
Citation (search report)
See references of WO 2008056069A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008056069 A1 20080515; AU 2007316520 A1 20080515; AU 2007316520 B2 20110929; BR PI0718577 A2 20140311; CA 2668650 A1 20080515; CA 2668650 C 20150526; CN 101611063 A 20091223; CN 101611063 B 20130220; EP 2094736 A1 20090902; FR 2908415 A1 20080516; FR 2908415 B1 20090123; JP 2010509425 A 20100325; JP 5389661 B2 20140115; KR 101478849 B1 20150102; KR 20090109084 A 20091019; MX 2009004969 A 20090521; RU 2009120214 A 20101220; RU 2456299 C2 20120720; US 2009263447 A1 20091022
DOCDB simple family (application)
FR 2007052245 W 20071025; AU 2007316520 A 20071025; BR PI0718577 A 20071025; CA 2668650 A 20071025; CN 200780043889 A 20071025; EP 07866489 A 20071025; FR 0609866 A 20061110; JP 2009535775 A 20071025; KR 20097011862 A 20071025; MX 2009004969 A 20071025; RU 2009120214 A 20071025; US 31869909 A 20090106