Global Patent Index - EP 2097520 A1

EP 2097520 A1 20090909 - A METHOD FOR PRODUCING N-TERMINAL METHIOINE FREE POLYPEPTIDES IN MICROBIAL HOST CELLS

Title (en)

A METHOD FOR PRODUCING N-TERMINAL METHIOINE FREE POLYPEPTIDES IN MICROBIAL HOST CELLS

Title (de)

VERFAHREN ZUR HERSTELLUNG VON POLYPEPTIDEN OHNE N-TERMINALES METHIONIN IN MIKROBIELLEN WIRTSZELLEN

Title (fr)

PROCEDE DE FABRICATION DE POLYPEPTIDES EXEMPTS DE METHIONINE N-TERMINALE DANS DES CELLULES HOTES MICROBIENNES

Publication

EP 2097520 A1 20090909 (EN)

Application

EP 07706183 A 20070112

Priority

  • IN 2007000012 W 20070112
  • IN 2217CH2006 A 20061130

Abstract (en)

[origin: WO2008065673A1] A method of making N-terminal methionine free polypeptide in a recombinant microbial host cell and pharmaceutical compositions along with one or more pharmaceutical excipients for management of various therapeutic disorders. Specifically, the invention relates to the production of N-terminal methionine free Streptokinase or human growth hormone by co expression with a protease enzyme in E.coli.

IPC 8 full level

A61K 38/27 (2006.01); A61K 38/48 (2006.01); C07K 14/315 (2006.01); C07K 14/61 (2006.01); C12N 9/70 (2006.01); C12N 15/18 (2006.01); C12N 15/57 (2006.01)

CPC (source: EP)

A61K 38/27 (2013.01); C07K 14/3153 (2013.01); C07K 14/395 (2013.01); C07K 14/61 (2013.01); C12N 9/52 (2013.01); C12P 21/02 (2013.01); C12P 21/06 (2013.01); C07K 2319/35 (2013.01); C07K 2319/50 (2013.01); Y02A 50/30 (2017.12)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2008065673 A1 20080605; EP 2097520 A1 20090909; EP 2097520 A4 20120704; MX 2009005764 A 20090824

DOCDB simple family (application)

IN 2007000012 W 20070112; EP 07706183 A 20070112; MX 2009005764 A 20070112