EP 2104674 A1 20090930 - THIOPHENE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
Title (en)
THIOPHENE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
Title (de)
THIOPHENANALOGA ZUR BEHANDLUNG ODER PRÄVENTION VON FLAVIVIRUS-INFEKTIONEN
Title (fr)
ANALOGUES DU THIOPHÈNE POUR LE TRAITEMENT OU LA PRÉVENTION D'INFECTIONS PAR UN FLAVIVIRUS
Publication
Application
Priority
- CA 2007002064 W 20071115
- US 85893906 P 20061115
Abstract (en)
[origin: WO2008058393A1] The present invention relates to compounds represented by formula IA or pharmaceutically acceptable salts and solvates thereof which are useful for treating flaviviridae viral infections wherein R<SUP>1</SUP> is C<SUB>1-6</SUB> alkyl or C<SUB>3-6</SUB> cycloalkyl; X is M is R<SUP>5</SUP> is cyclohexyl which is unsubstituted or substituted one or more times by R<SUP>13</SUP>; R<SUP>6</SUP> is or cyclohexyl which is substituted in the 4 position by R<SUP>14</SUP>; and Y, R<SUP>14a</SUP> and R<SUP>14</SUP> are as defined herein.
IPC 8 full level
C07D 333/40 (2006.01); A61K 31/381 (2006.01); A61P 31/12 (2006.01); C07D 333/38 (2006.01); C07D 409/12 (2006.01)
CPC (source: EP KR US)
A61K 31/381 (2013.01 - KR); A61K 38/005 (2013.01 - EP US); A61K 38/21 (2013.01 - EP US); A61P 1/16 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 31/14 (2017.12 - EP); A61P 31/20 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 39/06 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 333/38 (2013.01 - EP US); C07D 333/40 (2013.01 - EP KR US); C07D 409/12 (2013.01 - EP KR US); C07F 7/0812 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA HR MK RS
DOCDB simple family (publication)
WO 2008058393 A1 20080522; AP 2009004859 A0 20090630; AP 2579 A 20130129; AU 2007321677 A1 20080522; AU 2007321677 B2 20130411; BR PI0718915 A2 20131203; CA 2670260 A1 20080522; CN 101568538 A 20091028; CN 101568538 B 20120905; CN 102250074 A 20111123; CN 102675279 A 20120919; CO 6180430 A2 20100719; DK 2104674 T3 20130715; EA 016457 B1 20120530; EA 200970478 A1 20091230; EA 201101492 A1 20120928; EC SP099319 A 20090731; EP 2104674 A1 20090930; EP 2104674 A4 20100317; EP 2104674 B1 20130501; EP 2104674 B8 20131002; EP 2559691 A1 20130220; EP 2559692 A1 20130220; ES 2423219 T3 20130918; HK 1136562 A1 20100702; HK 1138569 A1 20100827; HR P20130658 T1 20130930; IL 198751 A0 20100217; JP 2010509376 A 20100325; JP 2012006966 A 20120112; JP 5290186 B2 20130918; KR 20090086081 A 20090810; MX 2009005185 A 20090707; NO 20092038 L 20090810; NZ 576780 A 20111222; NZ 596922 A 20130328; PL 2104674 T3 20131231; PT 2104674 E 20130726; RS 52874 B 20131231; SG 176488 A1 20111229; SI 2104674 T1 20130930; US 2008299080 A1 20081204; US 2012059170 A1 20120308; US 2012301430 A1 20121129; US 8003685 B2 20110823; US 8269014 B2 20120918; US 8658674 B2 20140225
DOCDB simple family (application)
CA 2007002064 W 20071115; AP 2009004859 A 20071115; AU 2007321677 A 20071115; BR PI0718915 A 20071115; CA 2670260 A 20071115; CN 200780048076 A 20071115; CN 201110131120 A 20071115; CN 201210081280 A 20071115; CO 09049318 A 20090514; DK 07845534 T 20071115; EA 200970478 A 20071115; EA 201101492 A 20071115; EC SP099319 A 20090511; EP 07845534 A 20071115; EP 12181993 A 20071115; EP 12181998 A 20071115; ES 07845534 T 20071115; HK 10103287 A 20100331; HK 10103863 A 20100421; HR P20130658 T 20130710; IL 19875109 A 20090514; JP 2009536570 A 20071115; JP 2011188667 A 20110831; KR 20097010572 A 20071115; MX 2009005185 A 20071115; NO 20092038 A 20090526; NZ 57678007 A 20071115; NZ 59692207 A 20071115; PL 07845534 T 20071115; PT 07845534 T 20071115; RS P20130306 A 20071115; SG 2011084498 A 20071115; SI 200731277 T 20071115; US 201113172477 A 20110629; US 201213571659 A 20120810; US 98433007 A 20071115