EP 2111394 A1 20091028 - COMPOUNDS WITH A COMBINATION OF CANNABINOID-CB1 ANTAGONISM AND SEROTONIN REUPTAKE INHIBITION
Title (en)
COMPOUNDS WITH A COMBINATION OF CANNABINOID-CB1 ANTAGONISM AND SEROTONIN REUPTAKE INHIBITION
Title (de)
VERBINDUNGEN MIT EINER KOMBINATION AUS CANNABINOID-CB1-ANTAGONISMUS UND SEROTONIN-WIEDERAUFNAHMEHEMMUNG
Title (fr)
COMPOSÉS ANTAGONISTES DES CANNABINOÏDES CB1 ET INHIBITEURS DE LA RÉABSORPTION DE LA SÉROTONINE
Publication
Application
Priority
- EP 2008050181 W 20080109
- EP 07100323 A 20070110
- US 87953307 P 20070110
- EP 08701345 A 20080109
Abstract (en)
[origin: WO2008084057A1] This invention relates to compounds with a combination of cannabinoid-CB<SUB>1</SUB>antagonism and serotonin reuptake inhibition to pharmaceutical compositions containing these compounds, to methods for preparing the compounds, methods for preparing novel intermediates useful for their synthesis, and methods for preparing compositions. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in psychosis, anxiety, depression, attention deficits, cognitive disorders, obesity, drug dependence, Parkinson's disease, Alzheimer's disease, pain disorders, neuropathic pain disorders and sexual disorders. In particular the invention relates to compoundsof the general formula (I): wherein the symbols have the meanings given in the specification.
IPC 8 full level
A61K 31/415 (2006.01); A61K 31/4155 (2006.01); A61K 31/4164 (2006.01); A61P 25/00 (2006.01); C07D 231/06 (2006.01); C07D 233/90 (2006.01); C07D 403/12 (2006.01)
CPC (source: EP KR)
A61K 31/415 (2013.01 - KR); A61K 31/4155 (2013.01 - KR); A61P 1/04 (2017.12 - EP); A61P 1/08 (2017.12 - EP); A61P 1/12 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 13/00 (2017.12 - EP); A61P 13/10 (2017.12 - EP); A61P 15/08 (2017.12 - EP); A61P 15/10 (2017.12 - EP); A61P 15/12 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 21/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/20 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 25/32 (2017.12 - EP); A61P 25/36 (2017.12 - EP); A61P 27/06 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 231/06 (2013.01 - EP KR); C07D 231/14 (2013.01 - EP KR); C07D 233/90 (2013.01 - EP KR); C07D 403/12 (2013.01 - EP KR)
Citation (search report)
See references of WO 2008084057A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008084057 A1 20080717; AU 2008204456 A1 20080717; CA 2671554 A1 20080717; EA 200970672 A1 20100226; EP 2111394 A1 20091028; IL 198999 A0 20100217; JP 2010515704 A 20100513; KR 20090103932 A 20091001
DOCDB simple family (application)
EP 2008050181 W 20080109; AU 2008204456 A 20080109; CA 2671554 A 20080109; EA 200970672 A 20080109; EP 08701345 A 20080109; IL 19899909 A 20090527; JP 2009545172 A 20080109; KR 20097016686 A 20080109