EP 2114882 A1 20091111 - METHOD FOR PRODUCING AMMONIUM HEXAFLUOROPHOSPHATES
Title (en)
METHOD FOR PRODUCING AMMONIUM HEXAFLUOROPHOSPHATES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON AMMONIUMHEXAFLUOROPHOSPHATEN
Title (fr)
PROCÉDÉ DE PRODUCTION DE D'HEXAFLUOROPHOSPHATES D'AMMONIUM
Publication
Application
Priority
- EP 2008050987 W 20080128
- EP 07101364 A 20070129
- EP 08708305 A 20080128
Abstract (en)
[origin: EP1950196A1] Preparing ammonium hexafluorophosphate compound (I) comprises: reacting quaternary ammonium compound (a) with a phosphate salt compound (b) in the presence of solvent to give (I), which is not a tiotropium hexafluorophosphate compound (II). Preparing ammonium hexafluorophosphate compound of formula (R4>-N+>(R3>)-R1>R2> PF6->) (I) comprises: reacting quaternary ammonium compound of formula (R4>-N+>(R3>)-R1>R2> X->) (a) with a phosphate salt compound of formula (Kat+>PF6->) (b) in the presence of solvent to give (I), which is not a tiotropium hexafluorophosphate compound of formula (II). R1>, R2>hydrocarbon, 1-10C-alkyl, 2-10C-alkenyl, 2-10C-alkinyl, 3-8C-cycloalkyl, 4-8C-cycloalkenyl, 6-8C-cycloalkinyl, 6-10C-aryl-1-6C-alkyl, 6-10C-aryl-2-6C-alkenyl, 6-10C-aryl-2-6C-alkinyl, 6-10C-aryl or heterocyclyl (optionally substituted); either R3>, R4>R1>; or NR3>R4>mono-, di- or tricyclic, 4-10C optionally saturated carbocycle (optionally substituted by O or S); X : anion; and Kat+>cation of Na+>, K+> (both preferred), Li+>, Mg2+> or Ca2+>. An independent claim is included for the ammonium hexafluorophosphate compound (I), which is not a tiotropium hexafluorophosphate compound (II). [Image].
IPC 8 full level
C07D 211/74 (2006.01); C07D 451/06 (2006.01); C07D 491/18 (2006.01)
CPC (source: EP US)
C07C 215/40 (2013.01 - EP US); C07D 211/74 (2013.01 - EP US); C07D 451/06 (2013.01 - EP US); C07D 491/18 (2013.01 - EP US)
Citation (search report)
See references of WO 2008092832A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 1950196 A1 20080730; CA 2676162 A1 20080807; EP 2114882 A1 20091111; JP 2010516616 A 20100520; US 2010063289 A1 20100311; WO 2008092832 A1 20080807
DOCDB simple family (application)
EP 07101364 A 20070129; CA 2676162 A 20080128; EP 08708305 A 20080128; EP 2008050987 W 20080128; JP 2009547654 A 20080128; US 52355308 A 20080128