Global Patent Index - EP 2121715 A4

EP 2121715 A4 20101229 - BLOCKING THE MIGRATION OR METASTASIS OF CANCER CELLS BY AFFECTING ADHESION PROTEINS AND THE USES OF NEW COMPOUNDS THEREOF

Title (en)

BLOCKING THE MIGRATION OR METASTASIS OF CANCER CELLS BY AFFECTING ADHESION PROTEINS AND THE USES OF NEW COMPOUNDS THEREOF

Title (de)

BLOCKIERUNG DER MIGRATION ODER METASTASE VON KREBSZELLEN DURCH ANHEFTUNG VON HAFTPROTEINEN SOWIE ANWENDUNGEN DER DARAUS GEWONNENEN NEUEN VERBINDUNGEN

Title (fr)

BLOCAGE DE LA MIGRATION OU DE LA METASTASE DES CELLULES CANCEREUSES PAR LA MODIFICATION DE PROTEINES D'ADHESION ET UTILISATIONS DE NOUVEAUX COMPOSES ASSOCIES

Publication

EP 2121715 A4 20101229 (EN)

Application

EP 08725693 A 20080215

Priority

  • US 2008002086 W 20080215
  • US 89038007 P 20070216
  • US 68319807 A 20070307
  • US 94770507 P 20070703
  • US 2007077273 W 20070830

Abstract (en)

[origin: WO2008133766A1] This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins or their receptors to cure disease, wherein the modulating comprises positive and negative regulating; wherein comprises inhibiting cancer growth, wherein the adhesion proteins or receptors comprise fibronectin, integrins family, Myosin, vitronectin, collagen, laminin, Glycosylation cell surface proteins, polyglycans, cadherin, heparin, tenascin, CD 54, CAM, elastin and FAK; wherein the methods, processes, compounds and compositions are also for anti-angiogenesis; wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, CNS cancer, melanoma cancer, renal cancer or cervix cancer.

IPC 8 full level

A61K 31/704 (2006.01); A61P 35/00 (2006.01)

CPC (source: EP)

A61K 31/04 (2013.01); A61P 1/02 (2017.12); A61P 1/04 (2017.12); A61P 3/06 (2017.12); A61P 3/08 (2017.12); A61P 3/12 (2017.12); A61P 5/06 (2017.12); A61P 5/38 (2017.12); A61P 7/02 (2017.12); A61P 7/04 (2017.12); A61P 7/10 (2017.12); A61P 9/00 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 9/14 (2017.12); A61P 11/04 (2017.12); A61P 11/06 (2017.12); A61P 11/10 (2017.12); A61P 11/16 (2017.12); A61P 13/02 (2017.12); A61P 13/12 (2017.12); A61P 15/08 (2017.12); A61P 17/04 (2017.12); A61P 19/02 (2017.12); A61P 19/08 (2017.12); A61P 21/00 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/04 (2017.12); A61P 25/06 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 31/22 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 35/04 (2017.12); A61P 39/06 (2017.12); A61P 43/00 (2017.12); C07H 15/256 (2013.01)

Citation (search report)

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  • [XY] VOUTQUENNE L ET AL: "Haemolytic acylated triterpenoid saponins from Harpullia austro-caledonica", PHYTOCHEMISTRY, PERGAMON PRESS, GB, vol. 66, no. 7, 1 April 2005 (2005-04-01), pages 825 - 835, XP004846755, ISSN: 0031-9422, DOI: 10.1016/J.PHYTOCHEM.2005.02.009
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  • [XI] DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; August 2003 (2003-08-01), HUANG W ET AL: "Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells", XP002609399, Database accession no. EMB-2003347021 & CHINESE JOURNAL OF LUNG CANCER 200308 CN, vol. 6, no. 4, August 2003 (2003-08-01), pages 254 - 257, ISSN: 1009-3419
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  • [XY] DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2004, OVESNA Z ET AL: "Pentacyclic triterpenoic acids: new chemoprotective compounds", XP002609502, Database accession no. PREV200500050812 & NEOPLASMA (BRATISLAVA), vol. 51, no. 5, 2004, pages 327 - 333, ISSN: 0028-2685
  • See references of WO 2008133766A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2008133766 A1 20081106; AU 2008244648 A1 20081106; CA 2676791 A1 20081106; CN 101772511 A 20100707; EP 2121715 A1 20091125; EP 2121715 A4 20101229; JP 2010519219 A 20100603; SG 178795 A1 20120329

DOCDB simple family (application)

US 2008002086 W 20080215; AU 2008244648 A 20080215; CA 2676791 A 20080215; CN 200880012065 A 20080215; EP 08725693 A 20080215; JP 2009550096 A 20080215; SG 2012011029 A 20080215