EP 2125893 A2 20091202 - OPTIMIZED CD40 ANTIBODIES AND METHODS OF USING THE SAME
Title (en)
OPTIMIZED CD40 ANTIBODIES AND METHODS OF USING THE SAME
Title (de)
OPTIMIERTE CD40-ANTIKÖRPER UND ANWENDUNGSVERFAHREN DAFÜR
Title (fr)
ANTICORPS CD40 OPTIMISÉS ET LEURS PROCÉDÉS D'UTILISATION
Publication
Application
Priority
- US 2008051812 W 20080123
- US 88629107 P 20070123
Abstract (en)
[origin: WO2008091954A2] The present invention describes antibodies that target CD40, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcyR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the antibodies of the invention.
IPC 8 full level
C07K 16/28 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); C07K 16/2878 (2013.01); C07K 2317/72 (2013.01); C07K 2317/73 (2013.01)
Citation (search report)
See references of WO 2008091954A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2008091954 A2 20080731; WO 2008091954 A3 20080904; WO 2008091954 A4 20081231; AU 2008207898 A1 20080731; AU 2008207898 B2 20120503; CA 2669412 A1 20080731; EP 2125893 A2 20091202; JP 2010514460 A 20100506; JP 5357778 B2 20131204
DOCDB simple family (application)
US 2008051812 W 20080123; AU 2008207898 A 20080123; CA 2669412 A 20080123; EP 08728147 A 20080123; JP 2009545016 A 20080123