EP 2136840 A2 20091230 - USE OF AN ANTI-CXCR4 ANTIBODY FOR TREATING CANCER
Title (en)
USE OF AN ANTI-CXCR4 ANTIBODY FOR TREATING CANCER
Title (de)
VERWENDUNG EINES ANTI-CXCR4-ANTIKÖRPERS ZUR KREBSBEHANDLUNG
Title (fr)
UTILISATION D'UN ANTICORPS ANTI-CXCR4 POUR LE TRAITEMENT DU CANCER
Publication
Application
Priority
- FR 2008000553 W 20080418
- FR 0702977 A 20070423
Abstract (en)
[origin: WO2008142303A2] The present invention relates to the use of at least one antibody, or a functional fragment thereof, capable of binding to the CXCR4 protein and thus of inhibiting tumour growth, for the preparation of a medicament for use in the treatment of cancer. The invention also relates to a composition for treating cancer, comprising, as active ingredient, at least one anti-CXCR4 antibody, or a functional fragment thereof, capable of binding to the CXCR4 protein and/or of inhibiting the angiogenic and/or proliferative activity thereof. More particularly, said antibodies consist of the MAB 173 antibody.
IPC 8 full level
A61K 39/395 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP US)
A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 16/2866 (2013.01 - EP US); A61K 2039/505 (2013.01 - EP US)
Citation (search report)
See references of WO 2008142303A2
Citation (examination)
- WO 2008060367 A2 20080522 - MEDAREX INC [US], et al
- ANONYMOUS: "MDA-MB-231 (ATCC(R) HTB-26TM) Homo sapiens mammary gland/breast", 16 December 2013 (2013-12-16), XP055093634, Retrieved from the Internet <URL:http://www.lgcstandards-atcc.org/products/all/HTB-26.aspx?geo_country=nl#characteristics> [retrieved on 20131216]
- N.N: "The mutation data was obtained from the Sanger Institute Catalogue Of Somatic Mutations", 16 December 2013 (2013-12-16), XP055093650, Retrieved from the Internet <URL:http://www.lgcstandards-atcc.org/~/media/CE379788822442FA8EC05617FDCF9ACD.ashx> [retrieved on 20131216]
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2915102 A1 20081024; FR 2915102 B1 20140516; CA 2683452 A1 20081127; EP 2136840 A2 20091230; JP 2010526044 A 20100729; US 2010150935 A1 20100617; WO 2008142303 A2 20081127; WO 2008142303 A3 20090122
DOCDB simple family (application)
FR 0702977 A 20070423; CA 2683452 A 20080418; EP 08787975 A 20080418; FR 2008000553 W 20080418; JP 2010504784 A 20080418; US 45102508 A 20080418