EP 2139456 A1 20100106 - PHARMACEUTICAL COMPOSITION COMPRISING CANDESARTAN CILEXETIL AND METHOD FOR MANUFACTURING THEREOF
Title (en)
PHARMACEUTICAL COMPOSITION COMPRISING CANDESARTAN CILEXETIL AND METHOD FOR MANUFACTURING THEREOF
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNG MIT CANDESARTAN-CILEXETIL UND HERSTELLUNGSVERFAHREN DAFÜR
Title (fr)
COMPOSITION PHARMACEUTIQUE COMPRENANT DU CANDÉSARTAN CILEXÉTIL ET PROCÉDÉ DE FABRICATION
Publication
Application
Priority
- PL 2008000026 W 20080328
- PL 38208007 A 20070328
- PL 38468008 A 20080312
Abstract (en)
[origin: WO2008118031A1] Stable pharmaceutical composition comprising candesartan cilexetil as the active pharmaceutical ingredient and graft copolymer of polyvinyl alcohol with polyethylene glycol as a stabilising agent. A method for manufacturing of pharmaceutical composition comprising candesartan cilexetil as the active pharmaceutical ingredient comprising the following steps: - a mixture comprising candesartan cilexetil, filler and binder is wet granulated with the solution of the graft copolymer of polyvinyl alcohol with polyethylene glycol acting as a granulating agent with optionally addition of a colourant, - the resulting granulate is dried, - a disintegrant and optionally another active pharmaceutical ingredient selected from diuretics, optionally a colourant, and a lubricant are added to the dried granulate and the resulting mixture is mixed and subsequently tableted.
IPC 8 full level
A61K 9/20 (2006.01)
CPC (source: EP)
A61K 9/2027 (2013.01); A61K 31/4184 (2013.01)
Citation (search report)
See references of WO 2008118031A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008118031 A1 20081002; EP 2139456 A1 20100106; PL 384680 A1 20080929; RU 2009139485 A 20110510
DOCDB simple family (application)
PL 2008000026 W 20080328; EP 08741767 A 20080328; PL 38468008 A 20080312; RU 2009139485 A 20080328