EP 2139522 A2 20100106 - MITOCHONDRIA TARGETED CATIONIC ANTI-OXIDANT COMPOUNDS FOR PREVENTION, THERAPY OR TREATMENT OF HYPER-PROLIFERATIVE DISEASE, NEOPLASIAS AND CANCERS
Title (en)
MITOCHONDRIA TARGETED CATIONIC ANTI-OXIDANT COMPOUNDS FOR PREVENTION, THERAPY OR TREATMENT OF HYPER-PROLIFERATIVE DISEASE, NEOPLASIAS AND CANCERS
Title (de)
AUF MITOCHONDRIEN GERICHTETE KATIONISCHE ANTIOXIDATIONSVERBINDUNGEN ZUR PRÄVENTION, THERAPIE ODER BEHANDLUNG VON HYPERPROLIFERATIVEN ERKRANKUNGEN, NEOPLASIEN UND KARZINOMEN
Title (fr)
COMPOSÉS ANTIOXYDANTS CATIONIQUES CIBLÉS SUR LES MITOCHONDRIES DESTINÉS À LA PRÉVENTION, À LA THÉRAPIE ET AU TRAITEMENT DES MALADIES HYPER-PROLIFÉRATIVES, DES NÉOPLASIES ET DES CANCERS
Publication
Application
Priority
- US 2008056035 W 20080306
- US 90523707 P 20070306
Abstract (en)
[origin: WO2008109740A2] The inventions disclosed include methods of treating cancers and related neoplasias, especially prostate cancer, with pharmaceutically acceptable salts comprising lipophilic cation moieties linked to nitroxide or linked to hydroxylamine anti-oxidant groups.
IPC 8 full level
A61K 31/4468 (2006.01); A61K 31/66 (2006.01); A61K 47/48 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C07D 207/46 (2006.01); C07D 211/94 (2006.01); C07F 9/54 (2006.01)
CPC (source: EP)
A61K 47/54 (2017.07); A61K 47/548 (2017.07); A61P 35/00 (2017.12); A61P 35/02 (2017.12); C07D 211/94 (2013.01); C07F 9/54 (2013.01); C07F 9/572 (2013.01); C07F 9/59 (2013.01)
Citation (search report)
See references of WO 2008109740A2
Citation (examination)
JANEZ MRAVLJAK ET AL: "Synthesis and Biological Evaluation of Spin-Labeled Alkylphospholipid Analogs", JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, no. 20, 1 October 2005 (2005-10-01), pages 6393 - 6399, XP055012330, ISSN: 0022-2623, DOI: 10.1021/jm050189v
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008109740 A2 20080912; WO 2008109740 A3 20081106; EP 2139522 A2 20100106
DOCDB simple family (application)
US 2008056035 W 20080306; EP 08731532 A 20080306