Global Patent Index - EP 2147104 A1

EP 2147104 A1 20100127 - USE OF AN ASPARTIC PROTEASE (NSP24) SIGNAL SEQUENCE FOR HETEROLOGOUS PROTEIN EXPRESSION

Title (en)

USE OF AN ASPARTIC PROTEASE (NSP24) SIGNAL SEQUENCE FOR HETEROLOGOUS PROTEIN EXPRESSION

Title (de)

VERWENDUNG EINER ASPARAGINPROTEASE (NSP24)-SIGNALSEQUENZ ZUR HETEROLOGEN PROTEINEXPRESSION

Title (fr)

UTILISATION D'UNE SÉQUENCE DE SIGNAUX DE PROTÉASE ASPARTIQUE (NSP24) POUR L'EXPRESSION D'UNE PROTÉINE HÉTÉROLOGUE

Publication

EP 2147104 A1 20100127 (EN)

Application

EP 08754611 A 20080521

Priority

  • US 2008006498 W 20080521
  • US 93107207 P 20070521
  • US 98443007 P 20071101
  • US 2008001646 W 20080206

Abstract (en)

[origin: WO2008150376A1] The invention relates to heterologous polypeptide expression and secretion by filamentous fungi and vectors and processes for expression and secretion of such polypeptides. More particularly, the invention discloses the use of a signal sequence form an aspartic protease obtained from Trichoderma and referred to as an NSP24 signal sequence.

IPC 8 full level

C12N 15/62 (2006.01); C12N 9/02 (2006.01); C12N 9/16 (2006.01); C12N 9/58 (2006.01); C12P 21/02 (2006.01)

CPC (source: EP US)

C12N 9/0061 (2013.01 - EP US); C12N 9/16 (2013.01 - EP US); C12N 9/58 (2013.01 - EP US); C12N 15/62 (2013.01 - EP US); C12P 21/02 (2013.01 - EP US); C07K 2319/02 (2013.01 - EP US); C07K 2319/036 (2013.01 - EP US)

Citation (search report)

See references of WO 2008150376A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA MK RS

DOCDB simple family (publication)

WO 2008150376 A1 20081211; DK 2147104 T3 20151214; EP 2147104 A1 20100127; EP 2147104 B1 20150909; US 2011027830 A1 20110203; US 8093016 B2 20120110

DOCDB simple family (application)

US 2008006498 W 20080521; DK 08754611 T 20080521; EP 08754611 A 20080521; US 60065208 A 20080521