EP 2147669 A2 20100127 - Rapidly dissolving robust dosage form
Title (en)
Rapidly dissolving robust dosage form
Title (de)
Schnelllösliche robuste Darreichungsform
Title (fr)
Formule de dosage robuste à dissolution rapide
Publication
Application
Priority
- EP 98914665 A 19980413
- US 4324297 P 19970416
- US 5788498 A 19980409
Abstract (en)
The invention relates to a hard, compressed, rapidly dissolvable dosage form adapted for direct oral dosing comprising: an active ingredient and a matrix including a non-direct compression filler and a lubricant. Said dosage form is adapted to rapidly dissolve in the mouth of a patient and thereby liberate the active ingredient. Preferably, the dosage form has a friability of about 2 % or less when tested according to the U.S.P. The dosage form also preferably has a hardness of 15-50 Newtons.
IPC 8 full level
A61K 9/20 (2006.01); A61K 9/00 (2006.01); A61K 9/26 (2006.01); A61K 9/46 (2006.01)
CPC (source: EP US)
A61K 9/0007 (2013.01 - EP US); A61K 9/0056 (2013.01 - EP US); A61K 9/2018 (2013.01 - EP US)
Citation (applicant)
- US 5225197 A 19930706 - BOLT IAN J [GB], et al
- US 5178878 A 19930112 - WEHLING FRED [US], et al
- US 5464632 A 19951107 - COUSIN GERARD [FR], et al
- US 5234957 A 19930810 - MANTELLE JUAN A [US]
- US 4940588 A 19900710 - SPARKS RANDALL T [US], et al
- US 5055306 A 19911008 - BARRY BRIAN W [GB], et al
- US 4613497 A 19860923 - CHAVKIN LEONARD [US]
- US 3962417 A 19760608 - HOWELL CHARLES J
- GB 189403160 A
- "Pharmaceutical Dosage Form: Tablets", vol. 1, 1989, pages: 372 - 376
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 9846215 A1 19981022; AU 6896998 A 19981111; AU 726336 B2 20001102; CA 2284663 A1 19981022; CA 2284663 C 20030617; DK 2147669 T3 20141117; DK 2147669 T4 20180312; DK 2266538 T3 20171023; EP 0975336 A1 20000202; EP 0975336 A4 20060201; EP 2147669 A2 20100127; EP 2147669 A3 20100310; EP 2147669 B1 20141029; EP 2147669 B2 20180117; EP 2266538 A2 20101229; EP 2266538 A3 20130213; EP 2266538 B1 20170816; ES 2525720 T3 20141229; ES 2525720 T5 20180405; ES 2647356 T3 20171221; HK 1137654 A1 20100806; JP 2001524956 A 20011204; JP 2008001726 A 20080110; JP 2012162558 A 20120830; JP 5072513 B2 20121114; PT 2147669 E 20141222; PT 2266538 T 20171120; US 6024981 A 20000215; US 6221392 B1 20010424
DOCDB simple family (application)
US 9807216 W 19980413; AU 6896998 A 19980413; CA 2284663 A 19980413; DK 09013477 T 19980413; DK 10011802 T 19980413; EP 09013477 A 19980413; EP 10011802 A 19980413; EP 98914665 A 19980413; ES 09013477 T 19980413; ES 10011802 T 19980413; HK 10102664 A 20100315; JP 2007249399 A 20070926; JP 2012092155 A 20120413; JP 54409398 A 19980413; PT 09013477 T 19980413; PT 10011802 T 19980413; US 46488299 A 19991216; US 5788498 A 19980409