EP 2162544 B1 20130417 - VECTORS FOR MULTIPLE GENE EXPRESSION
Title (en)
VECTORS FOR MULTIPLE GENE EXPRESSION
Title (de)
VEKTOREN FÜR DIE EXPRESSION MEHRERER GENE
Title (fr)
VECTEURS D'EXPRESSION GÉNIQUE DE PLUSIEURS SÉQUENCES
Publication
Application
Priority
- EP 2008051031 W 20080129
- EP 07360019 A 20070515
- EP 08708348 A 20080129
Abstract (en)
[origin: WO2008138648A1] The present invention provides a vector for expressing at least a first and a second nucleic acid molecules which exhibit a percentage of homology of approximately 80% or greater than 80% over a portion of 40 or more continuous nucleotides and wherein said first nucleic acid molecule and/or said second nucleic acid molecule is modified so as to reduce said percentage of homology to less than 75%. The present invention also relates to substantially isolated nucleic acid molecules comprising a nucleotide sequence as defined in any of SEQ ID NO: 9-15 and 66-69. It also provides a host cell and a pharmaceutical composition comprising such a nucleic acid molecule or vector as well as their use for therapeutic or preventive purposes.
IPC 8 full level
C12N 15/86 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP KR US)
A61K 39/12 (2013.01 - EP US); A61K 48/00 (2013.01 - KR); A61P 31/00 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 31/20 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/04 (2017.12 - EP); C07K 14/005 (2013.01 - EP US); C12N 7/00 (2013.01 - EP US); C12N 15/86 (2013.01 - KR); C12N 15/861 (2013.01 - KR); C12N 15/863 (2013.01 - KR); A61K 2039/53 (2013.01 - EP US); A61K 2039/70 (2013.01 - EP US); C12N 2710/20022 (2013.01 - EP US); C12N 2710/20034 (2013.01 - EP US); C12N 2710/24143 (2013.01 - EP US); C12N 2840/20 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2008138648 A1 20081120; AR 065075 A1 20090513; AU 2008250520 A1 20081120; AU 2008250520 B2 20131031; BR PI0810305 A2 20180710; CA 2686772 A1 20081120; CA 2686772 C 20150324; CN 101688223 A 20100331; CN 101688223 B 20130731; EP 2162544 A1 20100317; EP 2162544 B1 20130417; ES 2416361 T3 20130731; HK 1135731 A1 20100611; IL 201963 A0 20110801; IL 201963 A 20130930; JP 2010526547 A 20100805; JP 5474767 B2 20140416; KR 101514473 B1 20150422; KR 20100019432 A 20100218; MX 2009012272 A 20091201; PE 20090483 A1 20090520; RU 2009144898 A 20110620; RU 2462513 C2 20120927; TW 200844231 A 20081116; US 2010303838 A1 20101202; US 8337859 B2 20121225
DOCDB simple family (application)
EP 2008051031 W 20080129; AR P080100356 A 20080129; AU 2008250520 A 20080129; BR PI0810305 A 20080129; CA 2686772 A 20080129; CN 200880016061 A 20080129; EP 08708348 A 20080129; ES 08708348 T 20080129; HK 10103937 A 20100421; IL 20196309 A 20091105; JP 2010507858 A 20080129; KR 20097023308 A 20080129; MX 2009012272 A 20080129; PE 2008000210 A 20080129; RU 2009144898 A 20080129; TW 97103228 A 20080129; US 59997108 A 20080129