EP 2170064 A1 20100407 - 6.5-PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS
Title (en)
6.5-PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS
Title (de)
6,5-PYRROLOPIPERIDIN-TACHYKININ-REZEPTORANTAGONISTEN
Title (fr)
ANTAGONISTES 6,5-PYRROLOPIPÉRIDINE DES RÉCEPTEURS DE TACHYKININE
Publication
Application
Priority
- US 2008067270 W 20080618
- US 93686407 P 20070622
Abstract (en)
[origin: WO2009002770A1] The present invention is directed to certain hydroxymethyl ether hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, LUTS, depression, and anxiety.
IPC 8 full level
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61P 13/00 (2006.01); A61P 25/06 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01)
CPC (source: EP)
A61P 1/08 (2017.12); A61P 13/00 (2017.12); A61P 13/02 (2017.12); A61P 25/04 (2017.12); A61P 25/06 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12); C07D 471/04 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009002770 A1 20081231; AU 2008268667 A1 20081231; CA 2690737 A1 20081231; EP 2170064 A1 20100407; EP 2170064 A4 20100804; JP 2010530874 A 20100916
DOCDB simple family (application)
US 2008067270 W 20080618; AU 2008268667 A 20080618; CA 2690737 A 20080618; EP 08771300 A 20080618; JP 2010513364 A 20080618