EP 2170406 A2 20100407 - A method of hyperpolarizing a magnetic resonance agent
Title (en)
A method of hyperpolarizing a magnetic resonance agent
Title (de)
Verfahren zur Hyperpolarisierung eines Magnetresonanzmittels
Title (fr)
Procédé d' hyperpolarisation d'un agent à résonance magnétique
Publication
Application
Priority
- GB 2008002323 W 20080707
- GB 0713074 A 20070705
Abstract (en)
[origin: WO2009004357A2] The invention provides a method of hyperpolarising a magnetic resonance (MR) agent suitable for use in magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS) comprising the steps of: a. providing a solution comprising the MR agent suitable for use in MRI or MRS and at least one relaxation agent, the relaxation agent being a paramagnetic metal ion having an electron spin relaxation time of less than 1 x 10-10 seconds at 20°C; and b. exposing the solution to a temperature of less than 5 K and a magnetic field of at least 1 T. The relaxation agent may, for example, be dysprosium.
IPC 8 full level
G01R 33/28 (2006.01); A61K 49/10 (2006.01); G01R 33/56 (2006.01)
CPC (source: EP US)
A61K 49/103 (2013.01 - EP US); G01R 33/282 (2013.01 - EP US); G01R 33/5601 (2013.01 - EP US)
Citation (search report)
See references of WO 2009004357A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009004357 A2 20090108; WO 2009004357 A3 20090730; EP 2170406 A2 20100407; EP 2170406 B1 20131204; GB 0713074 D0 20070815; JP 2010532195 A 20101007; US 2010191097 A1 20100729; US 8679456 B2 20140325
DOCDB simple family (application)
GB 2008002323 W 20080707; EP 08775868 A 20080707; GB 0713074 A 20070705; JP 2010514130 A 20080707; US 66735208 A 20080707