EP 2170922 A1 20100407 - NUCLEIC ACID SAMPLE PREPARATION BY EXCLUSION OF DNA
Title (en)
NUCLEIC ACID SAMPLE PREPARATION BY EXCLUSION OF DNA
Title (de)
HERSTELLUNG EINER NUKLEINSÄUREPROBE DURCH DNA-AUSSCHLUSS
Title (fr)
PRÉPARATION D'UN ÉCHANTILLON D'ACIDE NUCLÉIQUE PAR EXCLUSION D'ADN
Publication
Application
Priority
- US 2008007899 W 20080625
- US 93722307 P 20070626
Abstract (en)
[origin: WO2009002511A1] Devices and methods are provided for separation of nucleic acids from waste materials in a biological sample, and then reacting the separated nucleic acids. In some embodiments, the methods comprise mixing a cell lysate having nucleic acids and waste materials with a waste-binding matrix to capture the cellular waste materials from the lysate. The waste-binding matrix can comprise hydrophilic and/or hydrophobic size- exclusion, ion-exchange particles. In some embodiments, the device comprises a substrate comprising a fluid processing pathway in which nucleic acid sample preparation occurs prior to a downstream genotyping reaction.
IPC 8 full level
C07H 21/00 (2006.01)
CPC (source: EP)
B01L 3/502753 (2013.01); C07H 21/00 (2013.01); B01L 7/52 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/087 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0677 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009002511 A1 20081231; EP 2170922 A1 20100407; EP 2170922 A4 20100811
DOCDB simple family (application)
US 2008007899 W 20080625; EP 08768775 A 20080625