EP 2173359 A2 20100414 - HEPARIN CONJUGATES AND METHODS
Title (en)
HEPARIN CONJUGATES AND METHODS
Title (de)
HEPARIN-KONJUGATE UND VERFAHREN
Title (fr)
CONJUGUÉS D'HÉPARINE ET PROCÉDÉS ASSOCIÉS
Publication
Application
Priority
- KR 2008003731 W 20080627
- US 82459407 A 20070629
Abstract (en)
[origin: WO2009005258A2] Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed between the bile acid and the heparin. Another embodiment includes a taheting moiety bonded to the heparin-bile acid conjugate through a spacer. Another illustartive heparin conjugate includes heparin covalently bonded to a sulfonated moiety, such as naphthaalene trisulfonate residue. A method of treating cancer includes administering a heparin conjugate to an individual in need thereof.
IPC 8 full level
A61K 31/715 (2006.01); A61K 31/54 (2006.01); A61L 33/00 (2006.01); C08L 5/10 (2006.01); C12N 9/50 (2006.01)
CPC (source: EP KR)
A61K 31/575 (2013.01 - KR); A61K 31/727 (2013.01 - KR); A61K 47/551 (2017.07 - EP); A61K 47/554 (2017.07 - EP); A61K 47/64 (2017.07 - EP); A61K 47/66 (2017.07 - EP); B82Y 5/00 (2013.01 - EP); C08B 37/0081 (2013.01 - EP); C08L 5/10 (2013.01 - EP)
Citation (search report)
See references of WO 2009005258A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009005258 A2 20090108; WO 2009005258 A3 20090226; EP 2173359 A2 20100414; KR 101027161 B1 20110405; KR 20090003128 A 20090109
DOCDB simple family (application)
KR 2008003731 W 20080627; EP 08778410 A 20080627; KR 20080061613 A 20080627