EP 2173430 A1 20100414 - SYSTEMS FOR PARTICLE RADIATION ENHANCED DELIVERY OF THERAPY
Title (en)
SYSTEMS FOR PARTICLE RADIATION ENHANCED DELIVERY OF THERAPY
Title (de)
SYSTEME ZUR DURCH PARTIKELSTRAHLUNG VERSTÄRKTEN VERABREICHUNG EINER THERAPIE
Title (fr)
SYSTÈMES D'ACCENTUATION DE L'ADMINISTRATION D'UNE THÉRAPIE PAR RAYONNEMENT DE PARTICULES
Publication
Application
Priority
- US 2008071653 W 20080730
- US 95277307 P 20070730
Abstract (en)
[origin: WO2009018383A1] Systems and methods for enhancing the selective targeting of agents (204) for preferential action at a target with reduced action with healthy tissue distal the target tissue. One or more agents (204) can be combined with nano scale structures/particles (202) for delivery to the target tissue. Appropriate bombardment with accelerated particle radiation, such as proton radiation, induces the release of the agents (204) at the target site. Nano carriers can be combined with therapeutic and/or imaging enhancement agents (204). Imaging of the target tissue can provide a verification of the delivered dose of particle radiation. Nanocarriers can be provided with an outer shell selected for biocompatibility and durability in the in vivo environment and further selected to provide a feedback mechanism in the treatment environment to accelerate the release of the agent (204) and reduce a total radiation dose needed for that release.
IPC 8 full level
A61N 1/40 (2006.01); A61N 5/10 (2006.01); B82Y 5/00 (2011.01)
CPC (source: EP)
A61N 5/10 (2013.01); B82Y 5/00 (2013.01); A61N 2005/1087 (2013.01); A61N 2005/1098 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009018383 A1 20090205; AU 2008282215 A1 20090205; AU 2008282215 B2 20140529; CA 2695985 A1 20090205; CA 2695985 C 20160628; EP 2173430 A1 20100414; EP 2173430 A4 20121121; JP 2010535084 A 20101118; JP 5331116 B2 20131030
DOCDB simple family (application)
US 2008071653 W 20080730; AU 2008282215 A 20080730; CA 2695985 A 20080730; EP 08826721 A 20080730; JP 2010520162 A 20080730