Global Patent Index - EP 2179045 A2

EP 2179045 A2 20100428 - CARTILAGE-SPECIFIC EXPRESSION

Title (en)

CARTILAGE-SPECIFIC EXPRESSION

Title (de)

KNORPELSPEZIFISCHE EXPRESSION

Title (fr)

EXPRESSION SPÉCIFIQUE AU CARTILAGE

Publication

EP 2179045 A2 (EN)

Application

EP 08763428 A

Priority

  • IB 2008052638 W
  • HU 0700457 A

Abstract (en)

[origin: WO2009004575A2] The invention provides an isolated nucleic acid comprising a nucleotide sequence for cartilage-specific expression, said sequence comprising the proximal promoter region of the matrilin-1 promoter and at least two cartilage-specific distal control elements capable of binding Sox9 positioned in 5' direction relative to the said proximal promoter region element. Vectors and transgenic animals are also provided.

IPC 8 full level

C12N 15/85 (2006.01); A01K 67/027 (2006.01)

CPC (source: EP)

A01K 67/0275 (2013.01); C07K 14/78 (2013.01); C12N 15/8509 (2013.01); A01K 2217/05 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0393 (2013.01); C12N 2830/008 (2013.01)

Citation (search report)

See references of WO 2009004575A3

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA MK RS

DOCDB simple family (publication)

WO 2009004575 A2 20090108; WO 2009004575 A3 20090305; EP 2179045 A2 20100428; HU 0700457 A2 20090528; HU 0700457 D0 20070828; HU 227614 B1 20110928

DOCDB simple family (application)

IB 2008052638 W 20080701; EP 08763428 A 20080701; HU 0700457 A 20070703