EP 2190853 A4 20110831 - HALIDE-FREE GLUCOSAMINE-ACIDIC DRUG COMPLEXES
Title (en)
HALIDE-FREE GLUCOSAMINE-ACIDIC DRUG COMPLEXES
Title (de)
HALOGENIDFREIE KOMPLEXE AUS GLUCOSAMIN UND EINEM SAUREN ARZNEIMITTEL
Title (fr)
COMPLEXES MEDICAMENTEUX ACIDES DE GLUCOSAMINE EXEMPTS D'HALOGENURE
Publication
Application
Priority
US 2007014610 W 20070622
Abstract (en)
[origin: WO2009002297A1] A complex of glucosamine having a purity of at least about 99 wt.% and a maximum halide content of about 0.01 wt.%, and a therapeutic drug having a pKa of less than 7. Preferably, the complex is stabilized by coating it with at least one pharmaceutically acceptable polymer comprising a water-soluble, water-immiscible and/or water-swellable homopolymer and/or copolymer. Suitable polymers include carboxypolymethylene homopolymers and copolymers; polyethylene glycol homopolymers and copolymers, povidone homopolymers and copolymers; polyacrylic acid homopolymers and copolymers; polyacrylamide homopolymers and copolymers; polysaccharides; and mixtures of two or more of the foregoing polymers. The resultant coated complex will be stable upon exposure to ambient temperature and/or the atmosphere. Suitable therapeutic drugs fall into the following classes: a- and ß- Adrenergic Agonists; Narcotic and Non-Narcotic Analgesics; Anorexics; Antiallergics; Antianginals; Antiarrhythmics; Antiasthmatics; Antibiotics; Anticoagulants; Anticonvulsants; Antidepressants; Antidiabetics; Antihistaminics; Antihypertensives; Nonsteroidal Antiinflammatories; Antimigraines; Antineoplastics; Antiparkinsonians; Antipsychotics; Antipyretics; Antispasmodics; Antithrombotics; Antiulceratives; Anxiolytics; Decongestants; Diuretics; Hepatoprotectants; Sedatives; and Vasodilators.
IPC 8 full level
C07H 5/06 (2006.01)
CPC (source: EP)
A61K 31/726 (2013.01); A61K 45/06 (2013.01); C07H 5/06 (2013.01)
Citation (search report)
- [XDI] US 5604206 A 19970218 - PARADIES HENRICH H [DE]
- [XDI] US 6291527 B1 20010918 - GIORGETTI PAOLO LUCA MARIA [IT]
- See references of WO 2009002297A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009002297 A1 20081231; CA 2690776 A1 20081231; EP 2190853 A1 20100602; EP 2190853 A4 20110831
DOCDB simple family (application)
US 2007014610 W 20070622; CA 2690776 A 20070622; EP 07835861 A 20070622