EP 2192899 B1 20141001 - TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS
Title (en)
TRANSITION METAL COMPLEXES OF CORROLES FOR PREVENTING CARDIOVASCULAR DISEASES OR DISORDERS
Title (de)
ÜBERGANGSMETALLKOMPLEXE VON CORROLEN ZUR PRÄVENTION VON KARDIOVASKULÄREN KRANKHEITEN ODER STÖRUNGEN
Title (fr)
COMPLEXES DE MÉTAUX DE TRANSITION DE CORROLES PERMETTANT DE PRÉVENIR DES TROUBLES OU DES MALADIES CARDIOVASCULAIRES
Publication
Application
Priority
- IL 2008001066 W 20080804
- US 96841607 P 20070828
Abstract (en)
[origin: WO2009027965A1] Transition metal complexes of amphiphilic/bipolar corroles, optically active isomers or pharmaceutically acceptable salts thereof are useful for prevention of a cardiovascular disease or disorder in a subject susceptible to develop such a cardiovascular disease or disorder.
IPC 8 full level
A61K 31/409 (2006.01); A61K 31/555 (2006.01); A61P 9/00 (2006.01); C07D 487/22 (2006.01)
CPC (source: EP US)
A61K 31/409 (2013.01 - EP US); A61K 31/555 (2013.01 - EP US); A61P 3/00 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/10 (2017.12 - EP); C07D 487/22 (2013.01 - EP US)
Citation (examination)
- HABER ADI ET AL: "Amphiphilic/Bipolar metallocorroles that catalyze the decomposition of reactive oxygen and nitrogen species, rescue lipoproteins from oxidative damage, and attenuate atherosclerosis in mice", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, WILEY VCH VERLAG, WEINHEIM, vol. 47, no. 41, 29 September 2008 (2008-09-29), pages 7896 - 7900, XP009109188, ISSN: 1433-7851, DOI: 10.1002/ANIE.200801149
- ADI HABER, MICHAEL AVIRAM, ZEEV GROSS: "Protecting the beneficial functionality of lipoproteins by 1-Fe, a corrole-based catalytic antioxidant", CHEMICAL SCIENCE, vol. 2, 2011, pages 295 - 302
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009027965 A1 20090305; AU 2008293376 A1 20090305; AU 2008293376 B2 20130711; CA 2698552 A1 20090305; CA 2698552 C 20141028; EP 2192899 A1 20100609; EP 2192899 B1 20141001; US 2011144078 A1 20110616; US 8791099 B2 20140729
DOCDB simple family (application)
IL 2008001066 W 20080804; AU 2008293376 A 20080804; CA 2698552 A 20080804; EP 08789742 A 20080804; US 67591508 A 20080804