EP 2195020 A1 20100616 - INACTIVATED INFLUENZA VACCINE
Title (en)
INACTIVATED INFLUENZA VACCINE
Title (de)
INAKTIVIERTE INFLUENZA-VAKZINE
Title (fr)
VACCIN ANTIGRIPPAL INACTIVÉ
Publication
Application
Priority
- EP 2008062694 W 20080923
- EP 07117050 A 20070924
- US 97456807 P 20070924
- EP 08804610 A 20080923
Abstract (en)
[origin: WO2009040343A1] The present invention is concerned with inactivated adjuvanted influenza vaccines. The present invention provides a vaccine that overcomes many of the drawbacks of existing inactivated influenza vaccines. The present invention provides an inactivated influenza vaccine, comprising beta propiolactone (BPL) inactivated whole influenza virus and comprising, as adjuvant, one or more mono-or disaccharide derivatives having at least one butnot more than N-1 fatty acid ester groups and, optionally, one but not more than N-1 sulphate ester groups, wherein N is the number of hydroxyl groups of the mono-or disaccharide from which the derivative is derived. The influenza virus in a vaccine according to the invention is preferably cell culture derived. Methods for producing influenza virus in cell culture are known in the art. The virus may be grown on cells of mammalian, avian, or human origen, such as Madin Darby Canine Kidney (MDCK), Vero, MDBK, CLDK, EBx or PerC6 cells.
IPC 8 full level
A61K 39/145 (2006.01); A61K 39/39 (2006.01)
CPC (source: EP)
A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/39 (2013.01); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 31/16 (2017.12); A61K 2039/5252 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55566 (2013.01); C12N 2760/16134 (2013.01)
Citation (search report)
See references of WO 2009040343A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009040343 A1 20090402; AR 068536 A1 20091118; BR PI0817230 A2 20170606; CN 101808659 A 20100818; EP 2195020 A1 20100616; TW 200927928 A 20090701
DOCDB simple family (application)
EP 2008062694 W 20080923; AR P080104130 A 20080924; BR PI0817230 A 20080923; CN 200880108502 A 20080923; EP 08804610 A 20080923; TW 97136110 A 20080919