EP 2195288 A2 20100616 - SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS
Title (en)
SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS
Title (de)
NIEDERMOLEKULARE ANTAGONISTEN DES BRADYKININ-B1-REZEPTORS
Title (fr)
ANTAGONISTE DE FAIBLE MASSE MOLÉCULAIRE DU RÉCEPTEUR B1 DE LA BRADYKININE
Publication
Application
Priority
- EP 2008007919 W 20080919
- EP 07018396 A 20070919
- EP 08802425 A 20080919
Abstract (en)
[origin: WO2009036996A2] Disclosed are compounds of formula (I) which are bradykinin B1 receptor (B1R) antagonists. These compounds are useful to treat diseases or relieve adverse symptoms associated with inflammation and pain. The invention encompasses novel compounds and acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases involving inflammation and pain.
IPC 8 full level
C07D 207/06 (2006.01); A61K 31/506 (2006.01); A61P 29/00 (2006.01); C07C 209/00 (2006.01); C07D 207/20 (2006.01); C07D 213/82 (2006.01); C07D 213/89 (2006.01); C07D 239/42 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01)
CPC (source: EP)
A61P 1/04 (2017.12); A61P 9/10 (2017.12); A61P 19/06 (2017.12); A61P 29/00 (2017.12); A61P 37/02 (2017.12); A61P 43/00 (2017.12); C07C 237/42 (2013.01); C07C 281/06 (2013.01); C07D 207/06 (2013.01); C07D 207/20 (2013.01); C07D 213/82 (2013.01); C07D 213/89 (2013.01); C07D 239/42 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07C 2601/02 (2017.04)
Citation (search report)
See references of WO 2009036996A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009036996 A2 20090326; WO 2009036996 A3 20090618; AR 068509 A1 20091118; AU 2008300822 A1 20090326; CA 2700051 A1 20090326; EP 2195288 A2 20100616; JP 2010539204 A 20101216; TW 200930710 A 20090716
DOCDB simple family (application)
EP 2008007919 W 20080919; AR P080104000 A 20080915; AU 2008300822 A 20080919; CA 2700051 A 20080919; EP 08802425 A 20080919; JP 2010525265 A 20080919; TW 97136164 A 20080919