EP 2205234 A4 20101222 - METHODS AND COMPOUNDS FOR TREATING RETINOL-RELATED DISEASES
Title (en)
METHODS AND COMPOUNDS FOR TREATING RETINOL-RELATED DISEASES
Title (de)
VERFAHREN UND VERBINDUNGEN ZUR BEHANDLUNG RETINOLBEDINGTER ERKRANKUNGEN
Title (fr)
PROCÉDÉS ET COMPOSÉS POUR LE TRAITEMENT DE MALADIES LIÉES AU RÉTINOL
Publication
Application
Priority
- US 2008076499 W 20080916
- US 97576507 P 20070927
- US 98132207 P 20071019
Abstract (en)
[origin: WO2009042444A2] Compounds that reduce serum retinol levels are used to treat ophthalmic conditions associated with the overproduction of waste products that accumulate during the course of the visual cycle. We describe methods, compounds, and compositions to treat, for example, the macular degenerations and dystrophies or to alleviate symptoms associated with such ophthalmic conditions.
IPC 8 full level
A61K 31/167 (2006.01); A61K 31/203 (2006.01); A61K 31/21 (2006.01); A61P 27/02 (2006.01)
CPC (source: EP)
A61K 31/167 (2013.01); A61K 31/20 (2013.01); A61K 31/21 (2013.01); A61P 27/02 (2017.12)
Citation (search report)
- [X] WO 2005092062 A2 20051006 - MYRIAD GENETICS INC [US], et al
- [X] US 4255152 A 19810310 - HEWITT BRIAN, et al
- [X] US 2526534 A 19501017 - BRITTON EDGAR C, et al
- [X] SANDHAM ET AL: "2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB LNKD- DOI:10.1016/J.BMCL.2007.05.019, vol. 17, no. 15, 1 August 2007 (2007-08-01), pages 4347 - 4350, XP022144702, ISSN: 0960-894X
- [X] ULVEN TROND ET AL: "Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits", JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, no. 23, November 2006 (2006-11-01), pages 6638 - 6641, XP002608837, ISSN: 0022-2623
- See references of WO 2009042444A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009042444 A2 20090402; WO 2009042444 A3 20090514; AU 2008305303 A1 20090402; CA 2699773 A1 20090402; CN 101873852 A 20101027; EP 2205234 A2 20100714; EP 2205234 A4 20101222; IL 204728 A0 20101130; JP 2010540541 A 20101224; KR 20100097098 A 20100902
DOCDB simple family (application)
US 2008076499 W 20080916; AU 2008305303 A 20080916; CA 2699773 A 20080916; CN 200880107835 A 20080916; EP 08834564 A 20080916; IL 20472810 A 20100325; JP 2010527024 A 20080916; KR 20107009129 A 20080916