EP 2213306 A4 20120829 - METHOD OF PRODUCING GRANULES CONTAINING MATERIAL OF NATURAL ORIGIN SUCH AS CHINESE ORTHODOX MEDICINE EXTRACT, CRUDE DRUG EXTRACT, NATURAL MATERIAL EXTRACT OR MIXTURE THEREOF AND METHOD OF PRODUCING TABLETS FROM THE GRANULES
Title (en)
METHOD OF PRODUCING GRANULES CONTAINING MATERIAL OF NATURAL ORIGIN SUCH AS CHINESE ORTHODOX MEDICINE EXTRACT, CRUDE DRUG EXTRACT, NATURAL MATERIAL EXTRACT OR MIXTURE THEREOF AND METHOD OF PRODUCING TABLETS FROM THE GRANULES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON GRANULAT MIT MATERIAL NATÜRLICHEN URSPRUNGS WIE ETWA EINEM EXTRAKT CHINESISCHER ORTHODOXER MEDIZIN, ROHDROGENEXTRAKT, NATURMATERIALEXTRAKT ODER MISCHUNG DARAUS UND VERFAHREN ZUR HERSTELLUNG VON TABLETTEN AUS DEM GRANULAT
Title (fr)
PROCÉDÉ DE PRODUCTION DE GRANULÉS CONTENANT UNE MATIÈRE D'ORIGINE NATURELLE TELLE QU'UN EXTRAIT PROPOSÉ PAR LA MÉDECINE TRADITIONNELLE CHINOISE, UN EXTRAIT DE MÉDICAMENT BRUT, UN EXTRAIT DE MATIÈRE NATURELLE OU UN MÉLANGE DE CEUX-CI ET PROCÉDÉ DE PRODUCTION DE COMPRIMÉS À PARTIR DES GRANULÉS
Publication
Application
Priority
- JP 2008066883 W 20080918
- JP 2007243046 A 20070919
Abstract (en)
[origin: EP2213306A1] [Problems] A preparation such as granules or tablets produced by using a material of a natural origin, for example, a Chinese orthodox medicine extract, a crude drug extract or a natural material extract having been dried and powdered shows a long disintegration time, has poor elution properties and largely differs in the behavior in the patient's body after dosing from decoctions or the like, though it is a designed as inherently having a decoction, etc. as the fundamental component. [Means for solving problems] A method of producing granules characterized by comprising adding to 100 parts by weight of a special calcium silicate, a material of a natural origin, which has been dispersed in a liquid or an aqueous solution containing water or an organic solvent, to give a solid content of 50 to 800 parts by weight, homogeneously mixing and dispersing by stirring the mixture, and then granulating the mixture by further stirring until the loose bulk density attains 0.3 to 0.8 g/ml.
IPC 8 full level
A61K 47/04 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 36/00 (2006.01)
CPC (source: EP)
A61K 9/2009 (2013.01); A61K 36/00 (2013.01)
Citation (search report)
- [E] EP 1990062 A1 20081112 - ASAHI BREWERIES LTD [JP] & WO 2007097333 A1 20070830 - ASAHI BREWERIES LTD [JP], et al
- [A] EP 1316316 A1 20030604 - TANABE SEIYAKU CO [JP]
- See references of WO 2009038145A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
EP 2213306 A1 20100804; EP 2213306 A4 20120829; CA 2700224 A1 20090326; JP 4976500 B2 20120718; JP WO2009038145 A1 20110106; KR 20100083767 A 20100722; WO 2009038145 A1 20090326
DOCDB simple family (application)
EP 08831431 A 20080918; CA 2700224 A 20080918; JP 2008066883 W 20080918; JP 2009533184 A 20080918; KR 20107005880 A 20080918