Global Patent Index - EP 2218777 A1

EP 2218777 A1 20100818 - Cellular compositions and methods for their preparation

Title (en)

Cellular compositions and methods for their preparation

Title (de)

Zelluläre Zusammensetzungen und Verfahren zu deren Herstellung

Title (fr)

Compositions cellulaires et procédé permettant de les préparer

Publication

EP 2218777 A1 20100818 (EN)

Application

EP 10162905 A 20060330

Priority

  • EP 06739994 A 20060330
  • US 11087905 A 20050421

Abstract (en)

The present invention relates to cell (e.g., hepatocyte, etc.) compositions and methods for their preparation and use. In particular, the invention concerns methods of processing preparations of such cells so as to permit their repeated cryopreservation and thawing while retaining substantial viability. The invention also concerns preparations of cells (e.g., hepatocytes) that have been repeatedly cryopreserved and thawed.

IPC 8 full level

C12N 5/071 (2010.01); A01N 1/02 (2006.01)

CPC (source: EP US)

C12N 5/067 (2013.01 - EP US)

Citation (applicant)

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Citation (search report)

  • [XY] OSTROWSKA ALINA ET AL: "Investigation of functional and morphological integrity of freshly isolated and cryopreserved human hepatocytes.", CELL AND TISSUE BANKING, vol. 1, no. 1, 2000, pages 55 - 68, XP002586195, ISSN: 1389-9333
  • [X] LEE K W ET AL: "The viability and function of cryopreserved hepatocyte spheroids with different cryopreservation solutions", TRANSPLANTATION PROCEEDINGS, ORLANDO, FL, US, vol. 36, no. 8, 1 October 2004 (2004-10-01), pages 2462 - 2463, XP004653032, ISSN: 0041-1345
  • [Y] SHIBATA YOSHIHIRO ET AL: "Prediction of hepatic clearance and availability by cryopreserved human hepatocytes: an application of serum incubation method.", DRUG METABOLISM AND DISPOSITION: THE BIOLOGICAL FATE OF CHEMICALS AUG 2002 LNKD- PUBMED:12124306, vol. 30, no. 8, August 2002 (2002-08-01), pages 892 - 896, XP002586196, ISSN: 0090-9556
  • [A] LLOYD TOM D R ET AL: "Cryopreservation of hepatocytes: a review of current methods for banking", CELL AND TISSUE BANKING, SPRINGER, NL, vol. 4, no. 1, 1 January 2003 (2003-01-01), pages 3 - 15, XP002416013, ISSN: 1389-9333

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA HR MK YU

DOCDB simple family (publication)

US 2005239042 A1 20051027; US 7604929 B2 20091020; AU 2006240454 A1 20061102; AU 2006240454 B2 20100722; AU 2010235914 A1 20101111; CA 2604693 A1 20061102; CA 2604693 C 20120814; CN 101501186 A 20090805; CN 101501186 B 20130619; CN 103275924 A 20130904; DK 1891208 T3 20120716; DK 2479259 T3 20240219; EP 1891208 A2 20080227; EP 1891208 B1 20120606; EP 2218777 A1 20100818; EP 2479259 A2 20120725; EP 2479259 A3 20120801; EP 2479259 B1 20231122; ES 2389099 T3 20121023; ES 2965619 T3 20240416; FI 2479259 T3 20240220; HK 1113689 A1 20081010; JP 2008539697 A 20081120; JP 5271076 B2 20130821; LT 2479259 T 20240312; PL 1891208 T3 20121130; PT 1891208 E 20120620; US 2010075294 A1 20100325; US 2010075295 A1 20100325; WO 2006115682 A2 20061102; WO 2006115682 A3 20090423

DOCDB simple family (application)

US 11087905 A 20050421; AU 2006240454 A 20060330; AU 2010235914 A 20101021; CA 2604693 A 20060330; CN 200680018373 A 20060330; CN 201310177718 A 20060330; DK 06739994 T 20060330; DK 12159369 T 20060330; EP 06739994 A 20060330; EP 10162905 A 20060330; EP 12159369 A 20060330; ES 06739994 T 20060330; ES 12159369 T 20060330; FI 12159369 T 20060330; HK 08109087 A 20080815; JP 2008507685 A 20060330; LT 12159369 T 20060330; PL 06739994 T 20060330; PT 06739994 T 20060330; US 2006011551 W 20060330; US 56834609 A 20090928; US 56844309 A 20090928