EP 2220077 A1 20100825 - 1, 2, 4 -OXADIAZOLE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
Title (en)
1, 2, 4 -OXADIAZOLE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
Title (de)
1, 2, 4 OXADIAZOLVERBINDUNGEN ZUR BEHANDLUNG VON AUTOIMMUNERKRANKUNGEN
Title (fr)
COMPOSÉS DE 1,2,4-OXADIAZOLE POUR LE TRAITEMENT DE MALADIES AUTO-IMMUNES
Publication
Application
Priority
- EP 2008067972 W 20081219
- GB 0725102 A 20071221
Abstract (en)
[origin: WO2009080730A1] The present invention relates to novel oxadiazole derivatives of formula (I) or a pharmaceutically acceptable salt thereof thereof. Compounds of formula (I) and their pharmaceutically acceptable salts are of use in the treatment of conditions or disorders which are mediated via the S1 P1 receptor. In particular the compounds of formula (I) and their pharmaceutically acceptable salts are of use in the treatment of multiple sclerosis, autoimmune diseases, chronic inflammatory disorders, asthma, inflammatory neuropathies, arthritis, transplantation, Crohn's disease, ulcerative colitis, lupus erythematosis, psoriasis, ischemia-reperfusion injury, solid tumours, and tumour metastasis, diseases associated with angiogenesis, vascular diseases, pain conditions, acute viral diseases, inflammatory bowel conditions, insulin and non-insulin dependant diabetes.
IPC 8 full level
C07D 413/04 (2006.01); A61K 31/553 (2006.01); A61P 37/00 (2006.01); C07D 413/14 (2006.01)
CPC (source: EP US)
A61P 1/04 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 11/00 (2017.12 - EP); A61P 11/06 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07D 413/04 (2013.01 - EP US); C07D 413/14 (2013.01 - EP US)
Citation (search report)
See references of WO 2009080730A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA MK RS
DOCDB simple family (publication)
WO 2009080730 A1 20090702; AU 2008339993 A1 20090702; BR PI0821696 A2 20150616; CA 2710055 A1 20090702; CN 101945865 A 20110112; CO 6290674 A2 20110620; CR 11576 A 20100903; DO P2010000193 A 20100815; EA 017669 B1 20130228; EA 201070783 A1 20101230; EP 2220077 A1 20100825; GB 0725102 D0 20080130; IL 206277 A0 20101230; JP 2011506572 A 20110303; KR 20100108567 A 20101007; MA 31923 B1 20101201; NZ 585995 A 20121221; UA 101348 C2 20130325; US 2010273770 A1 20101028; ZA 201003965 B 20110330
DOCDB simple family (application)
EP 2008067972 W 20081219; AU 2008339993 A 20081219; BR PI0821696 A 20081219; CA 2710055 A 20081219; CN 200880127354 A 20081219; CO 10074469 A 20100621; CR 11576 A 20100721; DO 2010000193 A 20100621; EA 201070783 A 20081219; EP 08863729 A 20081219; GB 0725102 A 20071221; IL 20627710 A 20100610; JP 2010538744 A 20081219; KR 20107016168 A 20081219; MA 32925 A 20100616; NZ 58599508 A 20081219; UA A201009201 A 20081219; US 74719808 A 20081219; ZA 201003965 A 20100603