EP 2224915 A4 20140122 - PHARMACEUTICAL COMPOSITION
Title (en)
PHARMACEUTICAL COMPOSITION
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNG
Title (fr)
COMPOSITIONS PHARMACEUTIQUES
Publication
Application
Priority
- US 2008087043 W 20081216
- US 793507 P 20071217
Abstract (en)
[origin: WO2009085778A1] Provided herein are pharmaceutical compositions comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions are also demonstrated.
IPC 8 full level
A61K 9/50 (2006.01); A61K 31/485 (2006.01); A61K 45/06 (2006.01)
CPC (source: EP)
A61K 9/5078 (2013.01); A61K 31/485 (2013.01); A61K 45/06 (2013.01)
Citation (search report)
- [XI] US 2004202717 A1 20041014 - MEHTA ATUL M [US]
- [I] WO 2004026283 A1 20040401 - ALPHARMA INC [US], et al
- [I] US 2005191244 A1 20050901 - BARTHOLOMAUS JOHANNES [DE], et al
- [A] WO 0158451 A1 20010816 - EURO CELTIQUE SA [LU], et al
- [A] WO 9733566 A2 19970918 - ALZA CORP [US]
- [XDPL] WO 2008063301 A2 20080529 - ALPHARMA INC [US], et al
- [XDPL] WO 2007149438 A2 20071227 - ALPHARMA INC [US], et al
- [IP] WO 2008027442 A2 20080306 - THERAQUEST BIOSCIENCES LLC [US], et al
- [EDL] WO 2009032270 A2 20090312 - ALPHARMA INC [US], et al
- [E] WO 2009079518 A1 20090625 - ALPHARMA PHARMACEUTICALS LLC [US], et al
- [E] WO 2009088673 A2 20090716 - ALPHARMA PHARMACEUTICALS LLC [US], et al
- [IP] JOHNSON F ET AL: "(236) Relative bioavailability of plasma naltrexone from crushed ALO-01 (an investigational, abuse-deterrent, extended-release, morphine sulfate formulation with sequestered naltrexone) to a naltrexone oral solution", JOURNAL OF PAIN, SAUNDERS, PHILADELPHIA, PA, US, vol. 9, no. 4, 1 April 2008 (2008-04-01), pages 35, XP025871409, ISSN: 1526-5900, [retrieved on 20080401], DOI: 10.1016/J.JPAIN.2008.01.157
- See references of WO 2009085778A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009085778 A1 20090709; AU 2008343267 A1 20090709; CA 2709950 A1 20090709; EP 2224915 A1 20100908; EP 2224915 A4 20140122
DOCDB simple family (application)
US 2008087043 W 20081216; AU 2008343267 A 20081216; CA 2709950 A 20081216; EP 08866252 A 20081216