Global Patent Index - EP 2225218 A1

EP 2225218 A1 20100908 - THIAZOLYLOXYPHENYLAMIDINES OR THIADIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES

Title (en)

THIAZOLYLOXYPHENYLAMIDINES OR THIADIAZOLYLOXYPHENYLAMIDINES AND THEIR USE AS FUNGICIDES

Title (de)

THIAZOLYLOXYPHENYLAMIDINE ODER THIADIAZOLYLOXYPHENYLAMIDINE UND DEREN VERWENDUNG ALS FUNGIZIDE

Title (fr)

THIAZOLYLOXYPHÉNYLAMIDINES OU THIADIAZOLYLOXYPHÉNYLAMIDINES ET LEUR UTILISATION EN TANT QUE FONGICIDE

Publication

EP 2225218 A1 20100908 (DE)

Application

EP 08868861 A 20081209

Priority

  • EP 2008010417 W 20081209
  • EP 07150360 A 20071221
  • EP 08868861 A 20081209

Abstract (en)

[origin: EP2072506A1] Thiadiazolyloxyphenylamidine or thiazolyloxyphenylamidine compounds (I) are new. Thiadiazolyloxyphenylamidine or thiazolyloxyphenylamidine compounds of formula (I) are new. Y 1>CR 7>or N; either R 1>1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12C-alkenyl or 4-12C-alkynyl (where in the ring system of all cyclic groups, one or more C atoms are replaced by heteroatoms of N, O, P or S, and substituted by one or more R1a, X, OR1a, S(R1a) 2, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2), H, SH or SR2a; and R 2>, R 3>1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12C-alkenyl, 4-12C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl, where in the ring system of all cyclic groups, one or more C atoms are replaced by heteroatoms of N, O, P or S, and substituted by one or more groups of R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; or R 2>R 3>, R 2>R 1>, R 1>R 3>4-7 membered ring containing heteroatoms of N, O, P or S, which is optionally replaced by one or more X, R1a, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; R 4>, R 5>H, X, CN, 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12C-alkenyl, 4-12C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl, where in the ring system of all cyclic groups, one or more C atoms are replaced by heteroatoms of N, O, P or S, and substituted by one or more groups of R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; R 6>X, CN, SH, SR2a, OR2a, (C=O)-R2a, 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12C-alkenyl, 4-12C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl, where in the ring system of all cyclic groups, one or more C atoms are replaced by heteroatoms of N, O, P or S, and substituted by one or more groups of OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; R 7>X, CN, SH, SR2a, OR2a, (C=O)-R2a, 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12C-alkenyl, 4-12C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl, where in the ring system of all cyclic groups, one or more C atoms are replaced by heteroatoms of N, O, P or S, and substituted by one or more groups of R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; n : 0-5; R1a : H or 1-12C-alkyl; and R2a : 1-12C-alkyl substituted by one or more groups from R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2. Independent claims are included for: (1) the preparation of (I); (2) a thiazolyl or thiadiazolylalcohol compound of formula (II); (3) a thiazolyl- or thiadiazolyl-derivative of formula (IV); (4) a thiazolyl- or thiadiazolylaminophenylether compound of formula (VIII); (5) a thiazolyl- or thiadiazolylaminophenylether compound of formula (VI); and (6) a process for the preparation of (II) or (IV) (in which Z is Cl and Y 1>is N) (preferred), comprising reacting cyclopropanecarboxamidine compound of formula (XX) with trichloromethyl thiohypochlorite. Z : a leaving group, preferably halo, triflate, mesylate, tosylate or SO 2Me. [Image] [Image] [Image] ACTIVITY : Antimicrobial; Fungicide; Antibacterial; Virucide; Herbicide; Antiparasitic. MECHANISM OF ACTION : None given.

IPC 8 full level

C07D 277/36 (2006.01); A01N 43/78 (2006.01); A01N 43/836 (2006.01); C07D 285/08 (2006.01)

CPC (source: EP US)

C07D 277/36 (2013.01 - EP US); C07D 285/08 (2013.01 - EP US)

Citation (search report)

See references of WO 2009083105A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA MK RS

DOCDB simple family (publication)

EP 2072506 A1 20090624; AR 069707 A1 20100210; CL 2008003712 A1 20091127; EP 2225218 A1 20100908; US 2010285957 A1 20101111; WO 2009083105 A1 20090709

DOCDB simple family (application)

EP 07150360 A 20071221; AR P080105466 A 20081216; CL 2008003712 A 20081212; EP 08868861 A 20081209; EP 2008010417 W 20081209; US 80950108 A 20081209