EP 2234622 A4 20110309 - METHODS FOR ENHANCING MUSCLE PERFORMANCE AND TONE
Title (en)
METHODS FOR ENHANCING MUSCLE PERFORMANCE AND TONE
Title (de)
VERFAHREN ZUR ERHÖHUNG VON MUSKELLEISTUNG UND MUSKELTONUS
Title (fr)
MÉTHODES AMÉLIORANT LES PERFORMANCES ET LE TONUS MUSCULAIRES
Publication
Application
Priority
- US 2008088466 W 20081229
- US 2007089124 W 20071228
- US 96685107 A 20071228
- US 8084108 P 20080715
Abstract (en)
[origin: WO2009086526A2] This disclosure concerns the use of agonists of AMP-activated protein kinase (AMPK) for improving exercise and modifying energy metabolism in a subject. The disclosure also relates to a combination of AMPK and peroxisome proliferator-activated receptor (PPAR) d agonists for improving exercise performance in a subject, methods for identifying substance-enhanced exercise performance in a subject, and methods for identifying compounds that affect the interaction of PPARd with exercise-induced kinases.
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/426 (2006.01); A61K 31/70 (2006.01); A61K 31/7056 (2006.01); A61K 45/06 (2006.01); A61P 21/06 (2006.01)
CPC (source: EP)
A61K 31/47 (2013.01); A61P 21/00 (2017.12); A61P 21/06 (2017.12); A61P 43/00 (2017.12)
Citation (search report)
- [XY] WO 0193874 A1 20011213 - UNIV BRIGHAM YOUNG [US], et al
- [XPI] WO 2008083330 A2 20080710 - SALK INST FOR BIOLOGICAL STUDI [US], et al
- [XP] NARKAR V A ET AL: "AMPK and PPAR.beta. Agonists Are Exercise Mimetics", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 134, no. 3, 8 August 2008 (2008-08-08), pages 405 - 415, XP002565786, ISSN: 0092-8674, [retrieved on 20080731], DOI: 10.1016/J.CELL.2008.06.051
- [Y] WANG YONG-XU ET AL: "Regulation of muscle fiber type and running endurance by PPARdelta", PLOS BIOLOGY, PUBLIC LIBRARY OF SCIENCE, US, vol. 2, no. 10, 1 October 2004 (2004-10-01), pages E294, XP002560117, ISSN: 1544-9173, DOI: 10.1371/JOURNAL.PBIO.0020294
- [Y] KRAEMER DAVID KITZ ET AL: "Role of AMP kinase and PPAR delta in the regulation of lipid and glucose metabolism in human skeletal muscle", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US, vol. 282, no. 27, 1 July 2007 (2007-07-01), pages 19313 - 19320, XP009143817, ISSN: 0021-9258
- See references of WO 2009086526A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009086526 A2 20090709; WO 2009086526 A3 20090903; AU 2008345009 A1 20090709; CA 2710764 A1 20090709; EP 2234622 A2 20101006; EP 2234622 A4 20110309; JP 2011507970 A 20110310
DOCDB simple family (application)
US 2008088466 W 20081229; AU 2008345009 A 20081229; CA 2710764 A 20081229; EP 08866040 A 20081229; JP 2010540930 A 20081229