EP 2243841 B1 20131127 - Method for manufacturing an enzymatic reagent ink
Title (en)
Method for manufacturing an enzymatic reagent ink
Title (de)
Verfahren zur Herstellung einer enzymatischen Reagenztinte
Title (fr)
Procédé de fabrication d'une encre réactive enzymatique
Publication
Application
Priority
US 42937609 A 20090424
Abstract (en)
[origin: EP2243841A1] A method for manufacturing an enzymatic reagent ink for use in analytical test strips (such as electrochemical-based analytical test strips configured for the determination of glucose in blood) includes determining a first relationship between wetability of a representative hydrophobic silica material (e.g., a hydrophobic fumed silica material) and at least a first calibration characteristic (for example, a calibration slope) of an analytical test strip that includes an enzymatic reagent ink containing the representative hydrophobic silica material. In the method, the first relationship defines a minimum wetability that provides an acceptable first calibration characteristic. The method also includes determining a second relationship defining wetability of a mixture of a particular hydrophobic silica material and a particular surfactant across a range of relative amount of the particular hydrophobic silica material and the particular surfactant and, subsequently, combining an amount of the particular hydrophobic silica material, an amount of the particular surfactant, and an amount of enzyme (such as glucose oxidase) to form an enzymatic reagent ink. Moreover, the amounts of the particular hydrophobic silica material and the particular surfactant are predetermined based on the second relationship to provide at least the minimum wetability defined by the first relationship.
IPC 8 full level
C12Q 1/00 (2006.01); C09D 11/00 (2006.01)
CPC (source: EP US)
C12Q 1/001 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR
DOCDB simple family (publication)
EP 2243841 A1 20101027; EP 2243841 B1 20131127; CA 2701572 A1 20101024; CA 2701572 C 20180306; CN 101871910 A 20101027; CN 101871910 B 20140806; ES 2446321 T3 20140307; HK 1148557 A1 20110909; JP 2010256357 A 20101111; JP 5676135 B2 20150225; US 2010270151 A1 20101028; US 8025788 B2 20110927
DOCDB simple family (application)
EP 10250820 A 20100423; CA 2701572 A 20100422; CN 201010165786 A 20100423; ES 10250820 T 20100423; HK 11102648 A 20110316; JP 2010099584 A 20100423; US 42937609 A 20090424