EP 2249646 A4 20130925 - DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS
Title (en)
DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS
Title (de)
PDE4-MUSCARIN-ANTAGONISTEN-DOPPELPHARMACOPHOREN
Title (fr)
PHARMACOPHORES DUALS, ANTAGONISTES DES RÉCEPTEURS MUSCARINIQUES ET INHIBITEURS DE L'ACTIVITÉ PDE4
Publication
Application
Priority
- US 2009033132 W 20090205
- US 2657408 P 20080206
Abstract (en)
[origin: WO2009100169A1] The present invention is directed to novel compounds of Formula's (I) - (VI), and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of and/or prophylaxis of respiratory diseases, including inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.
IPC 8 full level
C07D 471/04 (2006.01); A01N 43/42 (2006.01); A61K 31/437 (2006.01); A61P 11/08 (2006.01); A61P 37/06 (2006.01)
CPC (source: EP)
A61P 11/08 (2017.12); A61P 37/06 (2017.12); C07D 471/04 (2013.01)
Citation (search report)
- [I] WO 2005090352 A1 20050929 - GLAXO GROUP LTD [GB], et al
- See references of WO 2009100169A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009100169 A1 20090813; EP 2249646 A1 20101117; EP 2249646 A4 20130925
DOCDB simple family (application)
US 2009033132 W 20090205; EP 09707940 A 20090205