Global Patent Index - EP 2261366 A1

EP 2261366 A1 20101215 - Methods and nucleic acids for the analysis of CpG methylation associated with the development of prostate cell proliferative disorders

Title (en)

Methods and nucleic acids for the analysis of CpG methylation associated with the development of prostate cell proliferative disorders

Title (de)

Verfahren und Nukleinsäuren zur Analyse der CpG Methylierung, die mit der Entwicklung von mit der prostatischen Zellproliferation assozierten Krankheiten einhergeht

Title (fr)

Procédé et acides nucléiques pour l'analyse de la methylation CpG associé aux maladies prolifiques des cellules prostatiques

Publication

EP 2261366 A1 20101215 (EN)

Application

EP 10006026 A 20081111

Previously filed application

PCT/EP2008/009510 20081111 WO

Priority

  • EP 08851452 A 20081111
  • EP 07121408 A 20071123
  • EP 08166448 A 20081013
  • EP 10006026 A 20081111

Abstract (en)

The invention provides methods, nucleic acids and kits for detecting prostate cell proliferative disorders. The.invention discloses genomic sequences the methylation patterns of which have utility for the improved detection of said disorder, thereby enabling the improved diagnosis and treatment of patients.

IPC 8 full level

C12Q 1/68 (2006.01)

CPC (source: EP US)

C12Q 1/6886 (2013.01 - EP US); C12Q 2600/106 (2013.01 - US); C12Q 2600/118 (2013.01 - US); C12Q 2600/154 (2013.01 - EP US); C12Q 2600/158 (2013.01 - EP US)

Citation (search report)

  • [XI] WO 0177384 A2 20011018 - EPIGENOMICS AG [DE], et al
  • [X] US 6331413 B1 20011218 - ADLER DAVID A [US], et al
  • [X] EP 1764107 A1 20070321 - HARTMANN GUNTHER [DE]
  • [X] EP 1748083 A1 20070131 - ROCHE DIAGNOSTICS GMBH [DE], et al
  • [A] WANG X ET AL: "KLF8 transcription factor participates in oncogenic transformation", ONCOGENE, NATURE PUBLISHING GROUP, GB LNKD- DOI:10.1038/SJ.ONC.1209796, vol. 26, no. 3, 18 January 2007 (2007-01-18), pages 456 - 461, XP002540311, ISSN: 0950-9232, [retrieved on 20070710]
  • [A] SCHULZ W A ET AL: "Epigenetics of prostate cancer: beyond DNA methylation", JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 10, no. 1, January 2006 (2006-01-01), pages 100 - 125, XP002602398, ISSN: 1582-1838
  • [A] PAYNE S ET AL: "Urine is the preferred remote body fluid for early identification of prostate cancer using real-time PCR detection of DNA methylation markers", EJC SUPPLEMENTS, vol. 5, no. 4, September 2007 (2007-09-01), & 14TH EUROPEAN CANCER CONFERENCE (ECCO 14); BARCELONA, SPAIN; SEPTEMBER 23 -27, 2007, pages 282, XP002517341, ISSN: 1359-6349
  • [A] JERÓNIMO CARMEN ET AL: "A quantitative promoter methylation profile of prostate cancer", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 10, no. 24, 15 December 2004 (2004-12-15), pages 8472 - 8478, XP002485532, ISSN: 1078-0432
  • [A] BASTIAN P J ET AL: "Molecular Biomarker in Prostate Cancer: The Role of CpG Island Hypermethylation", EUROPEAN UROLOGY, ELSEVIER BV, NL, vol. 46, no. 6, 1 December 2004 (2004-12-01), pages 698 - 708, XP004645485, ISSN: 0302-2838
  • [A] DHANASEKARAN S M ET AL: "Delineation of prognostic biomarkers in prostate cancer", NATURE 20010823 MACMILLAN MAGAZINES LTD GB, vol. 412, no. 6849, 23 August 2001 (2001-08-23), pages 822 - 826, XP002517408

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2009065511 A2 20090528; WO 2009065511 A3 20091015; AU 2008328222 A1 20090528; CA 2706604 A1 20090528; EP 2261366 A1 20101215; EP 2261366 B1 20160127; EP 3078751 A1 20161012; EP 3078751 B1 20180801; ES 2565053 T3 20160331; ES 2694284 T3 20181219; US 2011136115 A1 20110609; US 2017067119 A1 20170309

DOCDB simple family (application)

EP 2008009510 W 20081111; AU 2008328222 A 20081111; CA 2706604 A 20081111; EP 10006026 A 20081111; EP 16152630 A 20081111; ES 10006026 T 20081111; ES 16152630 T 20081111; US 201615237160 A 20160815; US 74431808 A 20081111