EP 2265272 A4 20110511 - ADAPTIVE BIOCHEMICAL SIGNATURES
Title (en)
ADAPTIVE BIOCHEMICAL SIGNATURES
Title (de)
ADAPTIVE BIOCHEMISCHE SIGNATUREN
Title (fr)
SIGNATURES BIOCHIMIQUES ADAPTATIVES
Publication
Application
Priority
- US 2009037695 W 20090319
- US 7757508 A 20080319
- US 3801308 P 20080319
- US 15509109 P 20090224
Abstract (en)
[origin: WO2009117596A1] The present invention is related to methods of generating adaptive biochemical signatures in live cells and the use of said signatures to identify diagnostic and therapeutic modalities for human disease. The methods described herein comprise contacting a provocative agent to live cells and measuring and analyzing adaptive readouts. The methods of the invention may be used for therapeutic or diagnostic purposes.
IPC 8 full level
G01N 33/50 (2006.01); A61K 31/4745 (2006.01); A61K 31/513 (2006.01); G16B 40/30 (2019.01)
CPC (source: EP US)
G01N 33/5023 (2013.01 - EP); G16B 40/30 (2019.01 - EP US); G01N 2800/347 (2013.01 - EP); G16B 40/00 (2019.01 - EP)
Citation (search report)
- [X] DANIELPOUR D ET AL: "Cross-talk between IGF-I and TGF-beta signaling pathways", CYTOKINE AND GROWTH FACTOR REVIEWS, ELSEVIER LTD, GB, vol. 17, no. 1-2, 1 February 2006 (2006-02-01), pages 59 - 74, XP024987937, ISSN: 1359-6101, [retrieved on 20060201], DOI: 10.1016/J.CYTOGFR.2005.09.007
- [X] SARBASSOV DOS D ET AL: "Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB", MOLECULAR CELL, vol. 22, no. 2, April 2006 (2006-04-01), pages 159 - 168, XP002630237, ISSN: 1097-2765
- [X] WOO S-Y ET AL: "PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor [beta] expression and signaling", JOURNAL OF BIOLOGICAL CHEMISTRY 20070831 AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY INC. US, vol. 282, no. 35, 31 August 2007 (2007-08-31), pages 25604 - 25612, XP002630238, DOI: 10.1074/JBC.M704343200
- See references of WO 2009117596A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009117596 A1 20090924; CA 2718969 A1 20090924; EP 2265272 A1 20101229; EP 2265272 A4 20110511
DOCDB simple family (application)
US 2009037695 W 20090319; CA 2718969 A 20090319; EP 09723340 A 20090319