EP 2265638 A1 20101229 - STABLE CELL BINDING CHIMERIC PEPTIDES
Title (en)
STABLE CELL BINDING CHIMERIC PEPTIDES
Title (de)
STABILE ZELLBINDENDE CHIMÄRE PEPTIDE
Title (fr)
PEPTIDES CHIMÉRIQUES DE LIAISON CELLULAIRE STABLES
Publication
Application
Priority
- IL 2009000420 W 20090416
- US 4451308 P 20080414
Abstract (en)
[origin: WO2009128077A1] The present invention relates to novel family of homologous cell attachment chimeric peptides. In particular, the present invention relates to chimeric peptides, each comprising synthetic peptides comprising (a) an M-tide comprising an amino acid sequence that is at least 80% homologous to the amino acid sequence selected from the group consisting of: SEQ ID NO:1, 2 and 37; and (b) a core haptide comprising an amino acid sequence homologous to amino acid sequences at the carboxy termini of the and E chains of fibrinogen or other proteins comprising C-termini that are homologous to said fibrinogen sequences, wherein the M-tide and the core haptide originate from the same protein. The synthetic peptides are linked to one another thereby providing the chimeric peptides of the invention which does not occur in the native protein as a continuous sequence. The present invention further discloses pharmaceutical compositions comprising said chimeric peptides and uses thereof.
IPC 8 full level
C07K 14/75 (2006.01); A61K 38/36 (2006.01); A61L 27/22 (2006.01); C12N 15/62 (2006.01)
CPC (source: EP US)
A61L 27/22 (2013.01 - EP US); A61P 7/00 (2017.12 - EP); C07K 14/515 (2013.01 - EP US); C07K 14/75 (2013.01 - EP US); C07K 14/78 (2013.01 - EP US); C12N 15/62 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US)
Citation (search report)
See references of WO 2009128077A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2009128077 A1 20091022; EP 2265638 A1 20101229; US 2011111003 A1 20110512; US 8354111 B2 20130115
DOCDB simple family (application)
IL 2009000420 W 20090416; EP 09732123 A 20090416; US 93734409 A 20090416