EP 2268637 A1 20110105 - TRIAZOLOPYRIDINONE DERIVATIVES FOR USE AS STEAROYL COA DESATURASE INHIBITORS
Title (en)
TRIAZOLOPYRIDINONE DERIVATIVES FOR USE AS STEAROYL COA DESATURASE INHIBITORS
Title (de)
TRIAZOLPYRIDINONDERIVATE ZUR VERWENDUNG ALS STEAROYL-COA-DESATURASE-HEMMER
Title (fr)
DÉRIVÉS DE TRIAZOLOPYRIDINONE DESTINÉS À ÊTRE UTILISÉS COMME INHIBITEURS DE LA STÉAROYL-COA DÉSATURASE
Publication
Application
Priority
- US 2009039503 W 20090403
- US 4262508 P 20080404
Abstract (en)
[origin: US2009253738A1] The present invention discloses triazolopyridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
IPC 8 full level
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61P 3/00 (2006.01); A61P 3/06 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP US)
A61P 3/00 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 3/08 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 471/04 (2013.01 - EP US)
Citation (search report)
See references of WO 2009137201A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
US 2009253738 A1 20091008; US 8088792 B2 20120103; AU 2009244664 A1 20091112; BR PI0910987 A2 20170321; CA 2719288 A1 20091112; EP 2268637 A1 20110105; JP 2011516498 A 20110526; KR 20100132999 A 20101220; MX 2010010949 A 20110222; US 2012065227 A1 20120315; WO 2009137201 A1 20091112
DOCDB simple family (application)
US 41789109 A 20090403; AU 2009244664 A 20090403; BR PI0910987 A 20090403; CA 2719288 A 20090403; EP 09743188 A 20090403; JP 2011503219 A 20090403; KR 20107024841 A 20090403; MX 2010010949 A 20090403; US 2009039503 W 20090403; US 201113303763 A 20111123