EP 2269629 A3 20130911 - Compositions and methods for producing antigen-presenting cells
Title (en)
Compositions and methods for producing antigen-presenting cells
Title (de)
Zusammensetzungen und Verfahren zur Herstellung von Antigenpräsentierenden Zellen
Title (fr)
Compositions et procédés pour produire des cellules présentant des antigènes
Publication
Application
Priority
- EP 07016833 A 20010511
- EP 01933309 A 20010511
- US 20357100 P 20000511
Abstract (en)
[origin: WO0185920A2] The present invention relates to compositions and methods for producing antigen-presenting cells, in vitro, ex vivo or in vivo. This invention relates more particularly to methods and compositions for producing dendritic cells using interleukin-15, preferably in combination with a growth factor such as Granulocyte-Macrophage colony stimulating factor. This invention is particularly suited for producing immature dendritic cells and activated cells from precursors, in vitro, ex vivo or in vivo. The invention also relates to compositions for implementing these methods, as well as compositions comprising antigen-presenting cells and uses thereof. Dendritic cells or membrane vesicles derived therefrom have utility in many applications, including diagnostic, therapy, vaccination, research, screening and gene delivery.
IPC 8 full level
C07K 14/54 (2006.01); A61K 35/12 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01); C12N 1/38 (2006.01); C12N 5/0784 (2010.01); A61K 39/00 (2006.01)
CPC (source: EP US)
A61K 39/4611 (2023.05 - EP US); A61K 39/4615 (2023.05 - EP US); A61K 39/4622 (2023.05 - EP US); A61K 39/46482 (2023.05 - EP US); A61K 39/464838 (2023.05 - EP US); C12N 5/0639 (2013.01 - EP US); C12N 2501/052 (2013.01 - EP); C12N 2501/056 (2013.01 - EP); C12N 2501/15 (2013.01 - EP); C12N 2501/22 (2013.01 - EP); C12N 2501/23 (2013.01 - EP); C12N 2501/25 (2013.01 - EP); C12N 2501/52 (2013.01 - EP)
Citation (search report)
- [XD] WO 9903499 A1 19990128 - INST NAT SANTE RECH MED [FR], et al
- [X] WO 9726328 A1 19970724 - RPMS TECHNOLOGY LTD [GB], et al
- [X] BANCHEREAU J ET AL: "IMMUNOBIOLOGY OF DENDRITIC CELLS", ANNUAL REVIEW OF IMMUNOLOGY, ANNUAL REVIEWS INC, US, vol. 18, 2000, pages 767 - 811, XP001018258, ISSN: 0732-0582
- [X] ZITVOGEL L ET AL: "Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes", NATURE MEDICINE, NATURE PUBLISHING, CO, US, vol. 4, no. 5, 1 May 1998 (1998-05-01), pages 594 - 600, XP002085387, ISSN: 1078-8956
- [A] BANCHEREAU J & STEINMAN R M: "Dendritic cells and the control of immunity", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 392, no. 6673, 19 March 1998 (1998-03-19), pages 245 - 252, XP002134557, ISSN: 0028-0836
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0185920 A2 20011115; WO 0185920 A3 20020510; AT E371722 T1 20070915; AU 5974401 A 20011120; DE 60130206 D1 20071011; DE 60130206 T2 20080529; EP 1280889 A2 20030205; EP 1280889 B1 20070829; EP 2269629 A2 20110105; EP 2269629 A3 20130911; ES 2288952 T3 20080201
DOCDB simple family (application)
US 0115300 W 20010511; AT 01933309 T 20010511; AU 5974401 A 20010511; DE 60130206 T 20010511; EP 01933309 A 20010511; EP 10010087 A 20010511; ES 01933309 T 20010511