EP 2271763 A2 20110112 - METHODS OF EXPRESSING A POLYPEPTIDE IN THE BRAIN AND NUCLEIC ACID CONSTRUCTS CAPABLE OF SAME
Title (en)
METHODS OF EXPRESSING A POLYPEPTIDE IN THE BRAIN AND NUCLEIC ACID CONSTRUCTS CAPABLE OF SAME
Title (de)
VERFAHREN ZUR EXPRESSION EINES POLYPEPTIDS IM GEHIRN UND DAZU FÄHIGE NUKLEINSÄUREKONSTRUKTE
Title (fr)
PROCÉDÉS D'EXPRESSION D'UN POLYPEPTIDE DANS LE CERVEAU ET PRODUITS DE CONSTRUCTION D'ACIDE NUCLÉIQUE CAPABLES D'EFFECTUER CES PROCÉDÉS
Publication
Application
Priority
- IL 2009000341 W 20090325
- US 6493908 P 20080403
Abstract (en)
[origin: WO2009122401A2] A nucleic acid construct and construct system are disclosed. The nucleic acid construct and system comprise a regulatory sequence which regulates inducible expression of a polypeptide of interest, the regulatory sequence comprising a choroid plexus specific promoter, with the proviso that the choroid plexus specific promoter is not a transthyretin promoter. Pharmaceutical compositions comprising same and uses thereof are also disclosed.
IPC 8 full level
C12N 15/867 (2006.01)
CPC (source: EP)
C12N 15/86 (2013.01); A01K 2207/05 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A01K 2267/0356 (2013.01); C12N 2740/15043 (2013.01); C12N 2830/003 (2013.01); C12N 2830/008 (2013.01); C12N 2840/203 (2013.01)
Citation (search report)
See references of WO 2009122401A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2009122401 A2 20091008; WO 2009122401 A3 20100128; EP 2271763 A2 20110112
DOCDB simple family (application)
IL 2009000341 W 20090325; EP 09728297 A 20090325