EP 2274325 A4 20110525 - HUMAN G-CSF ANALOGS AND METHODS OF MAKING AND USING THEREOF
Title (en)
HUMAN G-CSF ANALOGS AND METHODS OF MAKING AND USING THEREOF
Title (de)
ANALOGA VON HUMANEM G-CSF UND VERFAHREN ZUR HERSTELLUNG UND ANWENDUNG DAVON
Title (fr)
ANALOGUE DU G-CSF HUMAIN ET SES PROCÉDÉS DE FABRICATION ET D'UTILISATION
Publication
Application
Priority
- US 2008070668 W 20080721
- US 12002208 A 20080513
Abstract (en)
[origin: WO2009139784A1] An analog of human granulocyte colony stimulating factor (hG-CSF analog) is disclosed. The hG-CSF analog comprises an amino acid sequence that differs from the wild-type hG-CSF sequence at position 17 and at least one other position, and is capable of preventing trophoblast cell apoptosis. Also disclosed is pharmaceutical compositions comprising the hG-CSF analog, polynucleotides encoding the hG-CSF analog, expression vectors containing the polynucleotides, host cells containing the expression vectors, as well as a method for preventing spontaneous abortion using the hG-CSF analog.
IPC 8 full level
C07K 14/535 (2006.01); C07K 1/107 (2006.01); C12N 15/27 (2006.01)
CPC (source: EP)
C07K 14/535 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [I] WO 2005039505 A2 20050506 - NORA LLC [US], et al
- [Y] WO 0104329 A1 20010118 - HANMI PHARM IND CO LTD [KR], et al
- [Y] EP 0459630 A2 19911204 - ICI PLC [GB]
- See references of WO 2009139784A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009139784 A1 20091119; EP 2274325 A1 20110119; EP 2274325 A4 20110525
DOCDB simple family (application)
US 2008070668 W 20080721; EP 08782147 A 20080721