Global Patent Index - EP 2285376 A1

EP 2285376 A1 20110223 - 6-AMINONICOTINAMIDE DERIVATIVES AS POTENT AND SELECTIVE HISTONE DEACETYLASE INHIBITORS

Title (en)

6-AMINONICOTINAMIDE DERIVATIVES AS POTENT AND SELECTIVE HISTONE DEACETYLASE INHIBITORS

Title (de)

6-AMINONICOTINAMIDDERIVATE ALS WIRKSAME UND SELEKTIVE HISTONDEACETYLASEHEMMER

Title (fr)

DÉRIVÉS DE 6-AMINONICOTINAMIDE FORMANT DES INHIBITEURS PUISSANTS ET SÉLECTIFS DE L HISTONE DÉSACÉTYLASE

Publication

EP 2285376 A1 20110223 (EN)

Application

EP 09747249 A 20090508

Priority

  • US 2009043302 W 20090508
  • US 5379508 P 20080516

Abstract (en)

[origin: WO2009140164A1] The present invention relates to certain 6-aminonicotinamide derivatives which are capable of inhibiting histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.

IPC 8 full level

A61K 31/44 (2006.01); C07D 401/00 (2006.01); C07D 405/00 (2006.01)

CPC (source: EP)

A61P 3/00 (2017.12); A61P 9/00 (2017.12); A61P 21/00 (2017.12); A61P 25/00 (2017.12); A61P 25/14 (2017.12); A61P 25/18 (2017.12); A61P 25/28 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 43/00 (2017.12); C07D 213/82 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA RS

DOCDB simple family (publication)

WO 2009140164 A1 20091119; EP 2285376 A1 20110223; EP 2285376 A4 20110720; JP 2011520891 A 20110721

DOCDB simple family (application)

US 2009043302 W 20090508; EP 09747249 A 20090508; JP 2011509573 A 20090508