EP 2286238 B1 20120321 - METHODS OF DISTINGUISHING BETWEEN GLUTAMINE FORMED BY CATAPLEROSIS OR PROTEOLYSIS
Title (en)
METHODS OF DISTINGUISHING BETWEEN GLUTAMINE FORMED BY CATAPLEROSIS OR PROTEOLYSIS
Title (de)
VERFAHREN ZUR UNTERSCHEIDUNG ZWISCHEN GLUTAMIN AUS KATAPLEROSE ODER PROTEOLYSE
Title (fr)
PROCÉDÉS PERMETTANT DE FAIRE LA DISTINCTION ENTRE LA GLUTAMINE FORMÉE PAR CATAPLÉROSE ET LA GLUTAMINE FORMÉE PAR PROTÉOLYSE
Publication
Application
Priority
- GB 2009001282 W 20090522
- GB 0809445 A 20080523
- PT 10458509 A 20090521
Abstract (en)
[origin: US2011079093A1] The present invention relates to methods of distinguishing between glutamine formed by cataplerosis or proteolysis. Sample from a subject may be assayed for deuteriated glutamine (following administration of deuteriated water (2H2O) and an agent that promotes excretion of glutamine from the subject). The methods are useful in clinical settings (e.g. to test whether or not patients are suffering from proteolysis or whether athletes are abusing anabolic drugs); and may be adapted for screening test compounds for cataplerotic or proteolytic activity.
IPC 8 full level
G01N 33/68 (2006.01)
CPC (source: EP US)
G01N 33/60 (2013.01 - EP US); G01N 33/6812 (2013.01 - EP US); G01N 33/6893 (2013.01 - EP US); G01N 33/94 (2013.01 - EP US); G01R 33/465 (2013.01 - EP US); G01N 24/08 (2013.01 - US); G01N 2500/00 (2013.01 - EP US); G01N 2500/02 (2013.01 - EP US); G01N 2800/04 (2013.01 - EP US); Y10T 436/24 (2015.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
US 2011079093 A1 20110407; US 9322893 B2 20160426; AT E550667 T1 20120415; EP 2286238 A1 20110223; EP 2286238 B1 20120321; ES 2384603 T3 20120709; GB 0809445 D0 20080702; PT 104585 A 20091123; PT 104585 B 20100705; WO 2009141619 A1 20091126
DOCDB simple family (application)
US 99393409 A 20090522; AT 09750097 T 20090522; EP 09750097 A 20090522; ES 09750097 T 20090522; GB 0809445 A 20080523; GB 2009001282 W 20090522; PT 10458509 A 20090521