Global Patent Index - EP 2286797 B1

EP 2286797 B1 20180314 - Dry powder composition comprising co-jet milled particles for pulmonary inhalation

Title (en)

Dry powder composition comprising co-jet milled particles for pulmonary inhalation

Title (de)

Trockenpulverzusammensetzung mit von einer Nebendüse gemahlenen Partikeln für die Lungeninhalation

Title (fr)

Composition de poudre sèche comprenant des particules moulues par jet pour inhalation pulmonaire

Publication

EP 2286797 B1 20180314 (EN)

Application

EP 10181354 A 20040915

Priority

  • GB 0321607 A 20030915
  • EP 04768542 A 20040915
  • GB 2004003996 W 20040915
  • GB 0321612 A 20030915
  • GB 0321608 A 20030915
  • GB 0409133 A 20040423

Abstract (en)

[origin: WO2005025541A2] Manufacture of Pharmaceutical Compositions The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active particles comprising a pharmaceutically active material for pulmonary inhalation, the method comprising a jet milling process.

IPC 8 full level

A61K 9/14 (2006.01); A61K 9/00 (2006.01); A61K 31/473 (2006.01); A61K 31/727 (2006.01)

CPC (source: EP US)

A61K 9/0075 (2013.01 - EP US); A61K 9/008 (2013.01 - EP US); A61K 9/16 (2013.01 - US); A61K 9/1617 (2013.01 - US); A61K 9/1623 (2013.01 - US); A61K 9/1694 (2013.01 - US); A61K 9/50 (2013.01 - US); A61K 31/473 (2013.01 - EP US); A61K 31/55 (2013.01 - EP US); A61K 31/5513 (2013.01 - EP US); A61K 31/727 (2013.01 - EP US); B02C 19/06 (2013.01 - US)

Citation (examination)

WO 9703649 A1 19970206 - CO ORDINATED DRUG DEV LTD [GB], et al

Citation (opposition)

Opponent : Teva UK Ltd

  • DE 10061932 A1 20021024 - PHARMATECH GMBH [DE]
  • WO 0200197 A1 20020103 - VECTURA LTD [GB], et al
  • EP 1048295 A2 20001102 - SHERMAN BERNARD CHARLES [CA]
  • WO 0189492 A1 20011129 - ASTRAZENECA AB [SE], et al
  • US 4895726 A 19900123 - CURTET BERNARD [FR], et al
  • WO 2004089374 A1 20041021 - VECTURA LTD [GB], et al
  • WO 2004093848 A2 20041104 - VECTURA LTD [GB], et al
  • WO 9703649 A1 19970206 - CO ORDINATED DRUG DEV LTD [GB], et al
  • WO 0243701 A2 20020606 - VECTURA LTD [GB], et al
  • G.S. BANKER AND C.T. RHODES: "Modern Pharmaceutics, Fourth Edition, Revised and Expanded", vol. 121, 2002, MARCEL DEKKER, article ANTHONY J. HICKEY: "Chapter 14- Delivery of Drugs by the Pulmonary Route", pages: 479 - 499, XP055539048
  • A.J. HICKEY: "Lung Deposition and Clearance of Pharmaceutical Aerosols: What Can Be Learned from Inhalation Toxicology and Industrial Hygiene?", AEROSOL SCIENCE AND TECHNOLOGY, vol. 18, no. 3, 1993, pages 290 - 304, XP055539066
  • ALFONSO R GENNARO: "Remington: The Science and Practice of Pharmacy, 20th Edition", 2000, LIPPINCOTT WILLIAMS & WILKINS, article ROBERT E O`CONNOR, JOSEPH B SCHWARTZ: "Chapter 37- Powders", pages: 681 - 685, XP055539086
  • R.J. MALCOMSON ET AL.: "Dry powder formulations for pulmonary delivery", PSTT, vol. 1, no. 9, December 1998 (1998-12-01), pages 394 - 398, XP001205507
  • N.R. LABIRIS ET AL.: "Pulmonary drug delivery.Part II: the role of inhalant dellivery devices and drug formulations in therapeutic effectiveness of aerosolized medications", BR. J. CLIN. PHARMACOL., vol. 56, 2003, pages 600 - 612, XP002440030
  • BYRON P R; DALBY R N; HICKEY A J: "OPTIMIZED INHALATION AEROSOLS I. THE EFFECTS OF SPHERICAL BAFFLE SIZE AND POSITION UPON THE OUTPUT OF SEVERAL PRESSURIZED NONAQUEOUS SUSPENSION FORMULATIONS", PHARMACEUTICAL RESEARCH,, vol. 6, 1989, pages 225 - 229, XP002944462
  • XIAN MING ZENG; ET AL: "Particle interactions in dry powder formulations for inhalation", 2001, TAYLOR & FRANCIS, London and New York, article "Chapter 5 (partly)", pages: 133 - 138, XP055412006

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2005025541 A2 20050324; WO 2005025541 A3 20050512; AU 2004271783 A1 20050324; CA 2539041 A1 20050324; DK 1663155 T3 20120326; EP 1663155 A2 20060607; EP 1663155 B1 20111130; EP 1670438 A2 20060621; EP 2286797 A2 20110223; EP 2286797 A3 20120523; EP 2286797 B1 20180314; EP 2286797 B2 20220126; GB 0321607 D0 20031015; JP 2007505832 A 20070315; PL 1663155 T3 20120430; PT 1663155 E 20120215; US 11103448 B2 20210831; US 2006257491 A1 20061116; US 2007081948 A1 20070412; US 2012138056 A1 20120607; US 2016158150 A1 20160609; US 2018177721 A1 20180628; US 8182838 B2 20120522; WO 2005025536 A2 20050324; WO 2005025536 A3 20050512; WO 2005025536 A8 20050623; WO 2005025536 A8 20061228; WO 2005025536 A9 20050811

DOCDB simple family (application)

GB 2004003942 W 20040915; AU 2004271783 A 20040915; CA 2539041 A 20040915; DK 04768542 T 20040915; EP 04768488 A 20040915; EP 04768542 A 20040915; EP 10181354 A 20040915; GB 0321607 A 20030915; GB 2004003996 W 20040915; JP 2006525904 A 20040915; PL 04768542 T 20040915; PT 04768542 T 20040915; US 201113337596 A 20111227; US 201514970261 A 20151215; US 201815903345 A 20180223; US 57114604 A 20040915; US 57188404 A 20040915