EP 2288622 A4 20120418 - MODIFIED FACTOR IX POLYPEPTIDES AND USES THEREOF
Title (en)
MODIFIED FACTOR IX POLYPEPTIDES AND USES THEREOF
Title (de)
MODIFIZIERTE FAKTOR-IX-POLYPEPTIDE UND ANWENDUNGEN DAVON
Title (fr)
POLYPEPTIDES MODIFIÉS DE FACTEUR IX ET LEURS UTILISATIONS
Publication
Application
Priority
- US 2009040813 W 20090416
- US 12456708 P 20080416
- US 4596108 P 20080417
Abstract (en)
[origin: WO2009137254A2] The invention relates to modified Factor IX polypeptides such as Factor IX polypeptides with one or more introduced glycosylation sites. The modified Factor IX polypeptides may exhibit increased in vitro or in vivo stability such as a longer plasma half-life. The invention also relates to methods of making modified Factor IX polypeptides, and methods of using modified Factor IX polypeptides, for example, to treat patients afflicted with hemophilia B.
IPC 8 full level
C07K 14/745 (2006.01); C12N 9/64 (2006.01)
CPC (source: EP)
A61P 7/04 (2017.12); C12N 9/644 (2013.01); C12Y 304/21022 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [X] WO 2007149406 A2 20071227 - NAUTILUS TECHNOLOGY LLC [US], et al
- See references of WO 2009137254A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2009137254 A2 20091112; WO 2009137254 A3 20100114; AU 2009244633 A1 20091112; BR PI0910702 A2 20160705; CA 2721683 A1 20091112; CN 102083856 A 20110601; CO 6311000 A2 20110822; CR 11737 A 20110207; DO P2010000311 A 20110228; EC SP10010551 A 20101130; EP 2288622 A2 20110302; EP 2288622 A4 20120418; IL 208718 A0 20101230; JP 2011517951 A 20110623; KR 20110005862 A 20110119; MX 2010011345 A 20110223; RU 2010146387 A 20120527; SG 189790 A1 20130531; SV 2010003704 A 20110221
DOCDB simple family (application)
US 2009040813 W 20090416; AU 2009244633 A 20090416; BR PI0910702 A 20090416; CA 2721683 A 20090416; CN 200980122784 A 20090416; CO 10128682 A 20101015; CR 11737 A 20101015; DO 2010000311 A 20101015; EC SP10010551 A 20101015; EP 09743241 A 20090416; IL 20871810 A 20101014; JP 2011505204 A 20090416; KR 20107025567 A 20090416; MX 2010011345 A 20090416; RU 2010146387 A 20090416; SG 2013028790 A 20090416; SV 2010003704 A 20101015