Global Patent Index - EP 2292262 A3

EP 2292262 A3 20111109 - Use of modified novirhabdoviruses to obtain vaccines

Title (en)

Use of modified novirhabdoviruses to obtain vaccines

Title (de)

Verwendung veränderte Novirhabdoviren zur Herstellung von Impfstoffe

Title (fr)

Utilisation de novirhabdovirus modifiés pour l'obtention de vaccins

Publication

EP 2292262 A3 20111109 (FR)

Application

EP 10182238 A 20030507

Priority

  • EP 03752789 A 20030507
  • FR 0205702 A 20020507

Abstract (en)

[origin: FR2839453A1] Use, as a pharmaceutical, of a recombinant novirhabdovirus (NRV) in which the gene (I) encoding the NV protein is inactivated. Independent claims are also included for the following: (1) recombinant NRV in which (I) is inactivated and contains in its genome at least one heterologous gene (II) that encodes a vaccinating antigen (Ag) of an organism pathogenic for fish; (2) cDNA (III) from the genome of the new recombinant NRV; (3) recombinant vector containing (III); and (4) vaccine containing an NRV in which (I) is inactivated.

IPC 8 full level

A61K 39/205 (2006.01); A61K 39/295 (2006.01); A61P 37/04 (2006.01); C07K 14/145 (2006.01); C12N 7/04 (2006.01); C12N 15/47 (2006.01); C12N 15/86 (2006.01)

CPC (source: EP US)

A61K 39/12 (2013.01 - EP US); A61K 39/205 (2013.01 - EP US); A61P 31/14 (2017.12 - EP); A61P 37/04 (2017.12 - EP); C07K 14/005 (2013.01 - EP US); C12N 7/00 (2013.01 - EP US); A61K 2039/5256 (2013.01 - EP US); A61K 2039/552 (2013.01 - EP US); C12N 2760/20022 (2013.01 - EP US); C12N 2760/20134 (2013.01 - EP US); C12N 2760/20143 (2013.01 - EP US); C12N 2760/20162 (2013.01 - EP US)

Citation (search report)

  • [A] EP 0051522 A1 19820512 - AGRONOMIQUE INST NAT RECH [FR]
  • [AD] BIACCHESI STEPHANE ET AL: "Recovery of NV knockout infectious hematopoietic necrosis virus expressing foreign genes.", JOURNAL OF VIROLOGY, vol. 74, no. 23, December 2000 (2000-12-01), December, 2000, pages 11247 - 11253, XP002233052, ISSN: 0022-538X
  • [A] JOHNSON MARC C ET AL: "Production of recombinant Snakehead rhabdovirus: The NV protein is not required for viral replication.", JOURNAL OF VIROLOGY, vol. 74, no. 5, March 2000 (2000-03-01), pages 2343 - 2350, XP002233053, ISSN: 0022-538X
  • [A] CONZELMANN K K: "NONSEGMENTED NEGATIVE-STRAND RNA VIRUSES: GENETICS AND MANIPULATION OF VIRAL GENOMES", ANNUAL REVIEW OF GENETICS, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 32, 1998, pages 123 - 162, XP008005872, ISSN: 0066-4197
  • [A] BOUDINOT PIERRE ET AL: "Combined DNA immunization with the glycoprotein gene of viral hemorrhagic septicemia virus and infectious hematopoietic necrosis virus induces double-specific protective immunity and nonspecific response in rainbow trout.", VIROLOGY, vol. 249, no. 2, 1 January 1998 (1998-01-01), pages 297 - 306, XP002233054, ISSN: 0042-6822
  • [A] NOONAN ET AL: "Recombinant infectious hematopoietic necrosis virus and viral hemorrhagic septicemia virus glycoprotein epitopes expressed in Aeromonas salmonicida induce protective immunity in rainbow trout (Oncorhynchus mykiss)", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, vol. 61, no. 10, 1 October 1995 (1995-10-01), pages 3586 - 3591, XP002087051, ISSN: 0099-2240
  • [T] THOULOUZE M-I ET AL: "Essential role of the NV protein of Novirhabdovirus for pathogenicity in rainbow trout", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 78, no. 8, 1 April 2004 (2004-04-01), pages 4098 - 4107, XP002406028, ISSN: 0022-538X, DOI: 10.1128/JVI.78.8.4098-4107.2004
  • [T] S. BIACCHESI ET AL: "Limited Interference at the Early Stage of Infection between Two Recombinant Novirhabdoviruses: Viral Hemorrhagic Septicemia Virus and Infectious Hematopoietic Necrosis Virus", JOURNAL OF VIROLOGY, vol. 84, no. 19, 1 October 2010 (2010-10-01), pages 10038 - 10050, XP055008333, ISSN: 0022-538X, DOI: 10.1128/JVI.00343-10
  • [T] E. GOMEZ-CASADO ET AL: "A comparative review on European-farmed finfish RNA viruses and their vaccines", VACCINE, vol. 29, no. 15, 1 March 2011 (2011-03-01), pages 2657 - 2671, XP055008332, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2011.01.097

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

FR 2839453 A1 20031114; FR 2839453 B1 20070511; AU 2003260540 A1 20031202; CA 2483712 A1 20031127; EP 1501543 A1 20050202; EP 2292262 A2 20110309; EP 2292262 A3 20111109; NO 20044901 L 20050117; NO 328272 B1 20100118; US 2006063250 A1 20060323; WO 03097090 A1 20031127

DOCDB simple family (application)

FR 0205702 A 20020507; AU 2003260540 A 20030507; CA 2483712 A 20030507; EP 03752789 A 20030507; EP 10182238 A 20030507; FR 0301413 W 20030507; NO 20044901 A 20041110; US 51343605 A 20050627