Global Patent Index - EP 2293776 B8

EP 2293776 B8 20160511 - FIBRINOGEN BEING FUNTIONALLY INTACT , STORAGE STABLE AND VIRUS-INACTIVATED

Title (en)

FIBRINOGEN BEING FUNTIONALLY INTACT , STORAGE STABLE AND VIRUS-INACTIVATED

Title (de)

LAGERSTABILES, FUNKTIONELL INTAKTES VIRUS-INAKTIVIERTES FIBRINOGEN

Title (fr)

FIBRINOGEN ÉTANT FONTIONELLEMENT INTACT, STABLE AU STOCKAGE ET INACTIVÉ DE VIRUS

Publication

EP 2293776 B8 (DE)

Application

EP 09768601 A

Priority

  • AT 2009000248 W
  • US 7483008 P

Abstract (en)

[origin: WO2009155626A2] Disclosed is a method for producing a fibrinogen solution from an aqueous solution that contains functionally intact fibrinogen and is contaminated with profibrin and/or fibrin monomers and/or fibrin monomer complexes and/or fibrin cleavage products. Said method is characterized in that the impurities are precipitated using a non-denaturing precipitating agent at a temperature ranging from -4° to +4° C and a Ca ion activity which does not exceed that of a 1,000 µM CaCl2 solution and are separated from the solution by means of a filtering or centrifugation process.

IPC 8 full level

A61K 9/00 (2006.01); C07K 14/75 (2006.01)

CPC (source: EP)

A61K 9/19 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); A61K 47/46 (2013.01); A61P 7/08 (2018.01); C07K 14/75 (2013.01); A61K 9/0019 (2013.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2009155626 A2 20091230; WO 2009155626 A3 20100225; CA 2728358 A1 20091230; CA 2728358 C 20160614; EP 2293776 A2 20110316; EP 2293776 B1 20160302; EP 2293776 B8 20160511; HU E028626 T2 20161228; US 2011114524 A1 20110519; US 8741846 B2 20140603

DOCDB simple family (application)

AT 2009000248 W 20090622; CA 2728358 A 20090622; EP 09768601 A 20090622; HU E09768601 A 20090622; US 200913000934 A 20090622