EP 2295089 B1 20180509 - BONE REPAIR PUTTY COMPRISING POROUS PARTICULATE AND CARRIER GEL
Title (en)
BONE REPAIR PUTTY COMPRISING POROUS PARTICULATE AND CARRIER GEL
Title (de)
PORÖSE PARTIKEL UND TRÄGERGEL ENTHALTENDE KNOCHENREPARATURPASTE
Title (fr)
MASTIC DE RÉPARATION OSSEUSE COMPRENANT UNE SUBSTANCE PARTICULAIRE POREUSE ET UN GEL SUPPORT
Publication
Application
Priority
- EP 03771937 A 20030728
- US 39985102 P 20020731
Abstract (en)
[origin: WO2004011053A1] A bone repair material is described that is of putty-like consistency, particularly useful for repairing dental bony defects such as those caused by bone loss resulting from moderate or severe periodontitis, augmenting of bony defects of the alveolar ridge, filling tooth extraction sites, or sinus elevation grafting. The repair material includes a porous, resorbable particulate that is bone-derived or derived from bone-like hydroxyapatite or synthetic hydroxyapatite; and, a resorbable carrier, such as high molecular weight polysaccharides, such as hyaluronic acid. A high concentration of particulate in the putty enhances bone repair and requires a high concentration of carrier to retain the putty at the defect site. For a particulate density of about 1.2 g/cc such as PEPGEN P-15(R) Bone Graft, a preferred formulation comprises about 55% percent by weight of the putty suspended in a hyaluronic acid gel of about 1.4 x 10<6> daltons molecular weight and a final concentration of about 56 mg/cc which material adheres to a bony periodontal defect and does not excessively expand or migrate from the defect when held in place by a conventional flap closure.
IPC 8 full level
A61K 31/717 (2006.01); A61K 33/42 (2006.01); A61L 24/00 (2006.01); A61L 27/00 (2006.01); A61L 27/46 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61P 19/00 (2006.01)
CPC (source: EP US)
A61L 24/0036 (2013.01 - EP US); A61L 24/0084 (2013.01 - EP US); A61L 27/46 (2013.01 - EP US); A61L 27/56 (2013.01 - EP US); A61L 27/58 (2013.01 - EP US); A61P 19/00 (2017.12 - EP); A61L 2430/02 (2013.01 - EP US)
Citation (examination)
EP 1208850 A1 20020529 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
Designated contracting state (EPC)
CH DE FR GB IT LI
DOCDB simple family (publication)
WO 2004011053 A1 20040205; AU 2003254211 A1 20040216; CA 2496449 A1 20040205; CA 2496449 C 20111115; EP 1525011 A1 20050427; EP 1525011 B1 20160817; EP 2295089 A2 20110316; EP 2295089 A3 20110504; EP 2295089 B1 20180509; JP 2005538757 A 20051222; JP 5449638 B2 20140319; US 2004062816 A1 20040401; US 7842300 B2 20101130
DOCDB simple family (application)
US 0323474 W 20030728; AU 2003254211 A 20030728; CA 2496449 A 20030728; EP 03771937 A 20030728; EP 10015208 A 20030728; JP 2004524911 A 20030728; US 62869203 A 20030728