EP 2296700 A2 20110323 - INTRANASAL ADMINISTRATION OF RECEPTOR-BINDING LIGANDS OR GENES ENCODING SUCH LIGANDS AS A THERAPEUTIC REGIMEN FOR MITIGATING INFECTIONS CAUSED BY RESPIRATORY PATHOGENS
Title (en)
INTRANASAL ADMINISTRATION OF RECEPTOR-BINDING LIGANDS OR GENES ENCODING SUCH LIGANDS AS A THERAPEUTIC REGIMEN FOR MITIGATING INFECTIONS CAUSED BY RESPIRATORY PATHOGENS
Title (de)
INTRANASALE VERABREICHUNG VON REZEPTORBINDENDEN LIGANDEN ODER SOLCHE LIGANDEN KODIERENDEN GENEN ALS THERAPIEPROGRAMM ZUR ABSCHWÄCHUNG VON DURCH ATEMWEGSKRANKHEITSERREGER HERVORGERUFENEN INFEKTIONEN
Title (fr)
ADMINISTRATION INTRANASALE DE LIGANDS LIANT UN RÉCEPTEUR OU DE GÈNES CODANT POUR LESDITS LIGANDS DANS LE CADRE D'UN SCHÉMA THÉRAPEUTIQUE VISANT À ATTÉNUER LES INFECTIONS PROVOQUÉES PAR DES AGENTS PATHOGÈNES RESPIRATOIRES
Publication
Application
Priority
- US 2009046132 W 20090603
- US 5841308 P 20080603
Abstract (en)
[origin: WO2010044921A2] The present invention relates to a receptor-binding ligand either administered intranasally or expressed following intranasal administration from a recombinant vector that expresses at least one therapeutic ligand which binds to a receptor necessary for infection by a respiratory pathogen. The receptor-binding ligand in the respiratory tract not only confers rapid protection as a therapeutic drug but also elicits long-term protective immunity as a vaccine against a respiratory pathogen. This regimen is not compromised by the emergence of drug resistance because the receptor for any pathogen can be blocked by the pathogen's own receptor-binding ligand.
IPC 8 full level
A61K 39/12 (2006.01); A61K 39/145 (2006.01); A61K 39/235 (2006.01)
CPC (source: EP)
A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/215 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/543 (2013.01); A61K 2039/58 (2013.01); C12N 2710/10343 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16234 (2013.01); C12N 2770/20022 (2013.01)
Citation (search report)
See references of WO 2010044921A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2010044921 A2 20100422; WO 2010044921 A3 20100715; EP 2296700 A2 20110323
DOCDB simple family (application)
US 2009046132 W 20090603; EP 09820933 A 20090603