EP 2297206 A1 20110323 - ANTI-CXCR4 ANTIBODIES
Title (en)
ANTI-CXCR4 ANTIBODIES
Title (de)
ANTI-CXCR4-ANTIKÖRPER
Title (fr)
ANTICORPS ANTI-CXCR4
Publication
Application
Priority
- US 2009043063 W 20090507
- US 5319208 P 20080514
Abstract (en)
[origin: WO2009140124A1] The present invention provides antibodies that bind human CXCR4 and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful in the treatment of tumorigenesis, including tumor growth, invasion, angiogenesis, or metastasis.
IPC 8 full level
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/18 (2017.12); A61P 11/00 (2017.12); A61P 13/08 (2017.12); A61P 13/12 (2017.12); A61P 17/00 (2017.12); A61P 25/00 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 35/04 (2017.12); C07K 16/2866 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01)
Citation (search report)
See references of WO 2009140124A1
Citation (examination)
ROBERTS S ET AL: "Generation of an antibody with enhanced affinity and specificity for its antigen by protein engineering", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, UNITED KINGDOM, vol. 328, 20 August 1987 (1987-08-20), pages 731 - 734, XP002987280, ISSN: 0028-0836, DOI: 10.1038/328731A0
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
WO 2009140124 A1 20091119; AU 2009246683 A1 20091119; CA 2724409 A1 20091119; CN 102027015 A 20110420; EA 201071300 A1 20110630; EP 2297206 A1 20110323; IL 208869 A0 20110131; JP 2011520885 A 20110721; KR 20100133012 A 20101220; MX 2010012435 A 20110503; ZA 201007955 B 20120425
DOCDB simple family (application)
US 2009043063 W 20090507; AU 2009246683 A 20090507; CA 2724409 A 20090507; CN 200980117230 A 20090507; EA 201071300 A 20090507; EP 09747210 A 20090507; IL 20886910 A 20101021; JP 2011509562 A 20090507; KR 20107025445 A 20090507; MX 2010012435 A 20090507; ZA 201007955 A 20101105