Global Patent Index - EP 2297206 A1

EP 2297206 A1 20110323 - ANTI-CXCR4 ANTIBODIES

Title (en)

ANTI-CXCR4 ANTIBODIES

Title (de)

ANTI-CXCR4-ANTIKÖRPER

Title (fr)

ANTICORPS ANTI-CXCR4

Publication

EP 2297206 A1 20110323 (EN)

Application

EP 09747210 A 20090507

Priority

  • US 2009043063 W 20090507
  • US 5319208 P 20080514

Abstract (en)

[origin: WO2009140124A1] The present invention provides antibodies that bind human CXCR4 and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful in the treatment of tumorigenesis, including tumor growth, invasion, angiogenesis, or metastasis.

IPC 8 full level

C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01)

CPC (source: EP)

A61P 1/00 (2017.12); A61P 1/18 (2017.12); A61P 11/00 (2017.12); A61P 13/08 (2017.12); A61P 13/12 (2017.12); A61P 17/00 (2017.12); A61P 25/00 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 35/04 (2017.12); C07K 16/2866 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01)

Citation (search report)

See references of WO 2009140124A1

Citation (examination)

ROBERTS S ET AL: "Generation of an antibody with enhanced affinity and specificity for its antigen by protein engineering", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, UNITED KINGDOM, vol. 328, 20 August 1987 (1987-08-20), pages 731 - 734, XP002987280, ISSN: 0028-0836, DOI: 10.1038/328731A0

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

Designated extension state (EPC)

AL BA RS

DOCDB simple family (publication)

WO 2009140124 A1 20091119; AU 2009246683 A1 20091119; CA 2724409 A1 20091119; CN 102027015 A 20110420; EA 201071300 A1 20110630; EP 2297206 A1 20110323; IL 208869 A0 20110131; JP 2011520885 A 20110721; KR 20100133012 A 20101220; MX 2010012435 A 20110503; ZA 201007955 B 20120425

DOCDB simple family (application)

US 2009043063 W 20090507; AU 2009246683 A 20090507; CA 2724409 A 20090507; CN 200980117230 A 20090507; EA 201071300 A 20090507; EP 09747210 A 20090507; IL 20886910 A 20101021; JP 2011509562 A 20090507; KR 20107025445 A 20090507; MX 2010012435 A 20090507; ZA 201007955 A 20101105