EP 2301938 A1 20110330 - CRYSTALLINE OF ESZOPICLONE, ITS COMPOSITION, PREPARATION AND USES THEREOF
Title (en)
CRYSTALLINE OF ESZOPICLONE, ITS COMPOSITION, PREPARATION AND USES THEREOF
Title (de)
ESZOPICLONKRISTALL, DESSEN ZUSAMMENSETZUNG, HERSTELLUNG UND ANWENDUNGEN DAVON
Title (fr)
CRISTAL D ESZOPICLONE, SA COMPOSITION, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
Publication
Application
Priority
- CN 2009000414 W 20090417
- CN 200810053548 A 20080618
Abstract (en)
The present invention disclosed a crystalline of S-zopiclone having a powder X-Ray diffraction spectrum using Cu-Ka radiation with characteristic peaks expressed in terms of 2¸ at about 11.08°, about 12.38°, about 15.86°, about 17.88°, about 19.98° and about 20.58°; a DSC thermogram with a peak at about 207.7°C and an infrared absorption spectrum (IR) with characteristic peaks at about 3078cm -1 , about 2942~2838cm -1 , about 2790cm -1 , about 1716cm -1 , about 1463cm -1 , about 1372cm -1 and about 757cm -1 . The present invention also disclosed a method for preparing the crystalline of eszopiclone, its pharmaceutical composition and its use in preparing a medicament for treating sleep disorder.
IPC 8 full level
A61K 31/4985 (2006.01); A61P 25/20 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP KR US)
A61K 31/4985 (2013.01 - EP KR US); A61P 25/20 (2017.12 - EP); C07D 487/04 (2013.01 - EP KR US)
Citation (third parties)
Third party :
CN 1854137 B 20100428 - TIANJIN KINSLY INVEST HOLDING GROUP CO LTD
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
Designated extension state (EPC)
AL BA RS
DOCDB simple family (publication)
EP 2301938 A1 20110330; EP 2301938 A4 20110622; AU 2009260075 A1 20091223; AU 2009260075 B2 20130314; AU 2009260075 B9 20130502; CA 2727979 A1 20091223; CA 2727979 C 20141104; CN 101607961 A 20091223; CN 101607961 B 20110810; JP 2011524379 A 20110901; JP 5946274 B2 20160706; KR 20110056480 A 20110530; RU 2010152782 A 20120810; RU 2492171 C2 20130910; US 2011098307 A1 20110428; US 8431577 B2 20130430; WO 2009152684 A1 20091223
DOCDB simple family (application)
EP 09765324 A 20090417; AU 2009260075 A 20090417; CA 2727979 A 20090417; CN 200810053548 A 20080618; CN 2009000414 W 20090417; JP 2011513845 A 20090417; KR 20117001325 A 20090417; RU 2010152782 A 20090417; US 99986709 A 20090417